Associate Research Scientist

Columbia University; New York (NY); On-site; USD 60,000 - 100,000; Full time

Job summary

An established industry player is looking for an Associate Research Scientist to join their innovative team in structural biology. This role involves conducting advanced Cryo-EM studies and crystallographic analyses of proteins, particularly those involved in RNA decapping. You will work closely with collaborators across institutions, mentor PhD students, and contribute to impactful research that drives scientific discovery. If you are passionate about molecular biology and biochemistry and want to make a difference in the field, this opportunity is perfect for you.

Qualifications

• Full set of experimental skills in structural biology required.
• PhD in Molecular Biology and Biochemistry is mandatory.

Responsibilities

• Conduct Cryo-EM studies of proteins involved in RNA decapping.
• Mentor PhD students and prepare reports for grant submissions.

Skills

Protein expression and purification

Protein crystallization

X-ray diffraction data collection

Cryo-EM data analysis

Structural analyses

Mutagenesis studies

Education

PhD in Molecular Biology and Biochemistry

Job description

Job Title: Associate Research Scientist

Job Number: 94534

Location: New York, US

Job Description

The Tong Lab in the Department of Biological Sciences is seeking an Associate Research Scientist. The incumbent should have a full set of experimental skills with structural biology, including protein expression and purification in bacteria and insect cells, protein crystallization, X-ray diffraction data collection and processing, crystal structure determination and refinement, cryo-EM grid preparation and screening, cryo-EM data analysis, cryo-EM model building and refinement, structural analyses and mutagenesis studies.

Responsibilities:

1. Cryo-EM studies of proteins involved in RNA decapping and possibly other biochemical processes.
2. Crystallographic studies of proteins involved in RNA decapping in plants and other organisms.
3. Detailed analyses of the structures that are obtained, and design mutagenesis experiments to assess the structural observations.
4. Working closely with collaborators, within Columbia and also with other institutions, on multi-faceted projects.
5. Preparing reports for grant submissions and drafting manuscripts detailing the results of studies for publication.
6. Mentoring PhD students and colleagues on related projects.

Qualifications

Minimum Degree Required: PhD

Field(s) of Specialization: Molecular Biology and Biochemistry

Application Deadline: 2025-05-01