Associate Principal Scientist, Statistical Programming

Merck & Co., Inc; United States; On-site; USD 144,373 - 224,100; Full time

Benefits offered by this job

Medical, dental, vision healthcare

Retirement benefits

Paid holidays and vacation

Job summary

Merck & Co., Inc is looking for an Associate Principal Scientist in Statistical Programming based in Rahway, NJ. The role requires significant expertise in SAS programming and clinical trials, focusing on high-quality statistical analysis for Oncology. Collaborate with teams to transform data into modeling analysis datasets and ensure high-quality deliverables.

Candidates must have a Bachelor's or Master's degree with extensive programming experience in clinical environments. The salary ranges from $144,373.00 to $224,100.00 per year, with attractive benefits including medical and retirement plans.

Qualifications

• 9+ years SAS programming experience in a clinical trial environment with a Bachelor's degree.
• 7+ years SAS programming experience in a clinical trial environment with a Master's degree.
• Ability to design and develop complex programming algorithms.

Responsibilities

• Provide statistical programming analysis for Oncology.
• Lead the creation of modeling datasets from original data sources.
• Support development of programming standards for deliverables.

Skills

SAS programming

Clinical trial programming

Data manipulation

Project management

Interpersonal skills

Education

Bachelor's degree in Computer Science, Statistics, or related field

Master's degree in Computer Science, Statistics, or related field

Tools

SAS/MACRO

SAS/GRAPH

Job description

Job Description

Associate Principal Scientist, Statistical Programming – Rahway, NJ

Responsibilities:

• Provide high quality statistical programming analysis and reporting deliverables for global PK modeling and simulation stakeholders Oncology therapeutic area.
• Gather and interpret user requirements, retrieve the required data, transform the data into modeling‑ready analysis datasets, and develop tables and figures according to the modeling analysis plans.
• Lead the data stewardship and take accountability for the creation of modeling data from original data source(s) to final modeling dataset.
• Act as a key collaborator with modelers, statisticians and other project stakeholders and execute project plans efficiently and oversee the work of other team members when opportunities arise.
• Programmatically synthesize preclinical/clinical data into analysis‑ready structures from varied data sources.
• Create modeling‑ready datasets by integrating PK, PD and covariate data.
• Produce tables and graphics for inclusion in study reports and regulatory submissions.
• Ensure programmatic traceability from data source to modeling result.
• Support the development of programming standards to enable efficient and high quality production of programming deliverables.
• Produce SAS transport files and associated documentation for regulatory submissions.
• Represent statistical programming on process improvement activities.

Education Requirements

• Must have a Bachelor's degree (or US equivalent) in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering, Pharmaceutical Sciences, or related field plus 9 years SAS programming experience in a clinical trial environment.
• OR Master's degree (or US equivalent) in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering, Pharmaceutical Sciences, or related field plus 7 years SAS programming experience in a clinical trial environment.

Position Requirements

• Must possess significant expertise in SAS and clinical trial programming including data steps, procedures, SAS/MACRO, SAS/GRAPH; and programming expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK parameters).
• Ability to design and develop complex programming algorithms; to efficiently manipulate clinical trial datasets including complex data preprocessing, filtering, and manipulation; demonstrated ability to work in an exploratory environment, handling non-standard data in a variety of formats with minimal requirements.
• Knowledge of pharmaceutical development processes.
• Ability to comprehend analysis plans which may describe methodology to be programmed.
• Understanding of statistical or pharmacokinetic terminology and concepts; and ability to implement statistical methods not currently available through commercial software packages also required.
• Must possess broad knowledge and significant experience in developing analysis and reporting deliverables for R&D projects (data, analyses, tables, graphics, listings).
• Ability to lead at a program level; ability to determine approach and ensure consistency and direct development of others when opportunities arise; ability to engage key stakeholders required.
• Must possess strong project management skills; excellent interpersonal skills; ability to negotiate and collaborate effectively; and excellent written, oral, and presentation skills.

Salary Range

$144,373.00 - $224,100.00 per year

Benefits

• Medical, dental, vision healthcare and other insurance benefits (for employee and family)
• Retirement benefits, including 401(k)
• Paid holidays, vacation, and compassionate and sick days

Compensation and Incentives

• Eligible for annual bonus and long‑term incentive, if applicable.

Location and Legal Requirements

• US and Puerto Rico residents only.
• San Francisco residents only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance.
• Los Angeles residents only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance.

Equal Employment Opportunity

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. We comply with all affirmative action requirements for protected veterans and individuals with disabilities.

Additional Employment Details

• Employee Status: Regular
• Relocation: No relocation
• VISA Sponsorship: No
• Travel Requirements: No Travel Required
• Flexible Work Arrangements: Not Applicable
• Shift: Not Indicated
• Valid Driving License: No
• Hazardous Material(s): n/a
• Job Posting End Date: 08/12/2026