Associate Principal Scientist, Regulatory Chemistry Manufacturing & Controls (CMC) Product Lead

Organon Comercializadora S de RL de C.V; Florham Park (NJ); Sur place; USD 140 000 - 190 000; Plein temps

Résumé du poste

Organon seeks an Associate Principal Scientist to develop and implement Regulatory CMC strategies for assigned products, leading the preparation and submission of CMC dossiers for lifecycle maintenance, registrations, and post-approval changes. This role may manage a team of 1–2 contributors or outsourcing partners to support project execution.

The candidate will lead global regulatory strategy, assess regulatory requirements, and ensure timely submissions while coordinating with manufacturing

Qualifications

• Bachelor's degree in a science, engineering, or a related field with relevant experience in biological/pharmaceutical research, manufacturing, testing or related field.
• Advanced degree (MS, MBA, Ph.D., PharmD) with relevant experience in the same areas.
• The candidate must be proficient in English; additional language skills are a plus.
• Proven experience in critically reviewing detailed scientific information to assess technical merits and support conclusions with data.
• Demonstrated superior oral and written communication skills in multicultural settings and ability to communicate complex issues succinctly.
• Demonstrated understanding of related fields (e.g., manufacturing, analytical, quality assurance) and ability to solve problems creatively.
• Demonstrated ability to generate innovative solutions to complex regulatory problems and communicate with stakeholders.
• Flexibility in responding to changing priorities or unexpected events.
• Demonstrated effective leadership, communication, interpersonal and negotiating skills.
• Ability to lead a team of direct or matrixed colleagues to deliver on commitments.

Responsabilités

• Serve as the CMC Product Lead for assigned products and deliver regulatory milestones through the product lifecycle.
• Lead development and execution of global regulatory strategy for CMC changes and documentation.
• Develop, author, and review CMC submission components for post-approval supplements, annual reports, and registrations.
• Provide regulatory leadership for product in-license/due diligence, divestment, or withdrawal activities.
• Collaborate with Manufacturing & Supply and external partners to ensure compliant change management.
• Manage CMC documentation including post-approval supplements, annual reports, and registrations.
• Apply regulatory knowledge to ensure approval and product supply continuity.
• Assess regulatory risks and propose mitigation strategies.
• Deliver milestones across product lifecycle and escalate issues as needed.

Connaissances

Proficient in English

Regulatory leadership

Strong communication

Team leadership

Description du poste

The Position

Reporting to the Director or Executive Director in Organon Regulatory Chemistry, Manufacturing and Controls (CMC), the Associate Principal Scientist is responsible for developing and implementing Regulatory Chemistry, Manufacturing & Controls (CMC) strategies for assigned small molecule or biological products in accordance with global regulations and guidances, and Organon procedures. The Associate Principal Scientist will lead the preparation and submission of CMC dossiers for life-cycle maintenance submissions, original registrations, and post-approval changes. The incumbent may manage a team of 1 to 2 individual contributors and/or outsourcing partners in support of project execution. The Associate Principal Scientist may also support project team goals and organizational initiatives, on an as needed basis.

Responsibilities

• Serve as the CMC Product Lead for assigned products and be accountable for the delivery of all regulatory milestones for assigned products through the product lifecycle.
• Lead development and execution of global product and project regulatory strategy(ies) by ensuring robust assessment of CMC changes, identification of global regulatory requirements and critical evaluation of supporting documentation to confirm acceptability and identification of potential risks.
• Execute regulatory strategies by leading the development, authoring and review of CMC submission components and documentation to support post-approval supplements, annual reports, registration renewals and responses to health authority questions per established business processes and systems.
• Provide regulatory leadership as needed to product in-license/due diligence review, product divestment and product withdrawal.
• Collaborate with Organon Manufacturing & Supply colleagues and external partners to support compliant execution of change management and conduct all activities with an unwavering focus on regulatory conformance.
• Manage execution of CMC documentation including post-approval supplements, annual reports, registration renewals and responses to health authority questions per established business processes and systems.
• Demonstrate an understanding of regulatory affairs and apply this understanding to the benefit of the company to ensure approval and Product supply continuity.
• Assess and communicate potential regulatory risks and propose mitigation strategies.
• Deliver all regulatory milestones for assigned products across the product lifecycle.
• Identify, communicate and elevate potential regulatory issues to Organon Regulatory CMC management, as needed.

Required Education, Experience and Skills

• Bachelor's degree, in a science, engineering, or a related field. Fields of study include Pharmacy, Chemistry, Chemical Engineering, Biology, Microbiology, Virology, Molecular Biology, or Biochemistry with at least 7 years of relevant experience including biological/pharmaceutical research, manufacturing, testing or a related field OR
• Advanced degree (MS, MBA, Ph.D., PharmD) with at least 4 years of relevant experience including biological/pharmaceutical research, manufacturing, testing or a related field.
• The candidate must be proficient in English; additional language skills are a plus.
• Proven experience in critically reviewing detailed scientific information to assess technical merits and suitability of scientific rationale to ensure information is presented clearly and conclusions are adequately supported by data.
• Demonstrated superior oral and written communication skills in multicultural settings and ability to communicate complex issues in a succinct and logical manner. Strong listening skills.
• Demonstrated sound understanding of related fields (e.g., manufacturing, analytical, quality assurance) and the ability to be creative and imaginative in the approach to new and diverse problem solving.
• Demonstrated ability to generate innovative solutions to complex regulatory problems and effectively work with and communicate to key stakeholders.
• Demonstrated flexibility in responding to changing priorities or dealing with unexpected events.
• Demonstrated effective leadership, communication, interpersonal and negotiating skills.
• Ability to lead a team of direct or matrixed colleagues to deliver on business commitments and project timelines.

Preferred Experience and Skills

• A candidate with experience in Regulatory CMC post-approval lifecycle management is preferred.

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Secondary Language(s) Job Description

Who We Are:

Organon delivers ingenious health solutions that enable people to live their best lives. We are a $6.5 billion global healthcare company focused on making a world of difference for women, their families and the communities they care for. We have an important portfolio and are growing it by investing in the unmet needs of Women's Health, expanding access to leading biosimilars and touching lives with a diverse and trusted portfolio of health solutions. Our Vision is clear: A be