Associate Principal Scientist, Health Economic and Decision Sciences

Merck & Co.; Boston (MA); Hybrid; USD 157,000 - 247,000; Full time

Job summary

Merck & Co. invites applications for an Associate Principal Scientist to join the Oncology health economic modeling team within BARDS/HEDS.

The role focuses on developing predictive and economic models to quantify the value of oncology products for patients, providers, and payers, and to support decision making across development and commercialization. The preferred location is West Point, PA, with hybrid work and opportunities to collaborate with internal and external partners on HTA

Qualifications

• HEOR experience beyond degree
• Experience in economic evaluation of oncology drugs
• Development and dissemination of health economic models
• Publications and HTA submissions
• Strong communication and collaboration skills

Responsibilities

• Lead BARDS HEDS work as Value and Implementation lead for health economic models
• Use discovery, real-world data, trials, and published information for models
• Advance quantitative modeling and simulation with internal and external partners
• Develop and maintain global health economic models and tools
• Support country/regional adaptations and stakeholder communications
• Disseminate results via congresses and journals
• Collaborate with external thought leaders and internal teams
• Stay aware of data, methods, and IT tools to enhance capabilities
• Share best practices across the enterprise

Skills

Data Management

Economic Modeling

Health Economics

Health Technology Assessment

Oncology

Research

Stakeholder Relationships

Education

PhD or Master’s in Health Economics or related quantitative field

Job description

Job Description

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science", great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

We have an exciting opportunity for a new Associate Principal Scientist to join our Oncology health economic modeling team in the Health Economic and Decision Sciences group. The preferred location for this role is West Point, PA; although alternate locations may be considered, including Rahway, NJ; Boston, MA; the UK, and Switzerland. - Hybrid and flexible work arrangements are possible, consistent with local office and country policies.

The Health Economic and Decision Sciences (HEDS) department is part of our Company's Biostatistics and Research Decision Sciences (BARDS) organization. BARDS is responsible for strategic design and analysis to enable informed decision making in the discovery, development and delivery of our Company's innovative products, and is a leader in quantitative scientific methodology and its application to enable the targeting, discovery, development, manufacturing, and marketing of drugs and vaccines for the benefit of patients and global public health.

In collaboration with internal and external partners, the BARDS-HEDS department specifically provides strategic and technical leadership to enable patient access, measure and quantify the value of our Company's products, inform internal and external decisions, and shape methodology and external health policy and practice. This position will focus on health economic modeling for oncology products.

Role

Under the direction of an HEDS Senior Director, the Associate Principal Scientist provides strategic development and use of industry-leading predictive and economic models to enhance our understanding of disease and to quantify and communicate the value of our oncology products to patients, providers, and payers.

• Serve as the BARDS HEDS lead for one or more Value and Implementation teams to develop health economic, disease, and predictive models to enable business insights for the product.
• Utilize discovery, real world evidence, clinical trial and published data, and publicly available information and tools to provide economic and integrated models to answer key questions in all phases of drug and vaccine development - Phase I through loss of data exclusivity.
• Advance the use of integrated quantitative approaches, focusing on economic, disease, and predictive modeling and simulation in partnership with other internal groups and external organizations.
• Development and maintenance of health quality global health economic models and tools in-house or in collaboration with external vendors to provide critical business insights and fully demonstrate the value of our company's products.
• Support and training of HEDS models and tools to support country/regional team adaptations and communications with external stakeholders.
• Dissemination of health economic data via presentations at congresses and publications in scientific journals.
• Work closely with external collaborators (clinical/economic thought leaders, payer/HTA experts, alliance partners) and internal cross-functional teams to ensure that new methodologies, models and advanced analytics are fully utilized for our products.
• Maintain awareness of external data, modeling methodologies and IT tools to collaborate across relevant internal stakeholders to enhance our Company's capabilities in health economic modeling, simulation, and data visualization.
• Ensure sharing of work product and relevant best practices across our Company's enterprise.

Education

• PhD (preferred) or Master's degree, in Health Economics, Biostatistics, Health Services Research, Actuarial Sciences, Operations Research or a closely related quantitative field

Required Experience and Skills:

• Relevant work experience in health economics and outcomes research (HEOR) beyond PhD or Master's degree
• Knowledge and experience in economic evaluation of oncology drugs and interventions
• Expertise and solid hands‑on experience in the conceptualization, design, development and dissemination of health economic model approaches to enable internal and external decisions
• Track record of submissions to Health Technology Assessment bodies and research publications in conferences and peer‑reviewed journals
• Strong interpersonal, organizational and communication skills with ability to interact with individuals from a variety of disciplines
• Understanding of the market access environment and challenges in the US and key international markets

Required Skills:

Data Management, Economic Modeling, Health Economics, Health Economics Evaluation, Health Technology Assessment (HTA), Oncology, Researching, Stakeholder Relationship Management, Strategic Planning

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. - As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. - For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The primary location for this posting is:

USA - Pennsylvania - West Point

Where required by law, the compensation range for this role is provided below.

The salary range for the primary location of this role is:

$156,900.00 - $247,000.00

This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

Additional location(s):

Please note the salary range above applies to the Primary Location of the position. Where a role has other listed locations, different compensation guidelines may apply. You may find the salary ranges for additional locations below. If the salary range is not listed for the location you are applying to, our Talent Acquisition team will provide further information to you relevant to your location.

San Francisco Residents Only:

-We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:

-We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

n/a

Job Posting End Date:

10/26/2026

*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:

R413148