Associate Principal Scientist Biology Onsite

Neomorph, Inc.; San Diego (CA); On-site; USD 180,000 - 260,000; Full time

Benefits offered by this job

Industry-competitive compensation

Annual bonus target

Stock options

401K plan

Career advancement opportunities

Monthly town halls

Job summary

Neomorph, Inc. is seeking an experienced drug discovery biologist to lead programs from early discovery through IND-enabling studies.

You will collaborate across functions to shape project strategy and drive data-driven go/no-go decisions, advancing therapeutic candidates with robust SAR-enabled assays and strong scientific leadership. The role requires a track record in preclinical drug discovery, team leadership, and the ability to thrive in a fast-paced research environment within a San

Qualifications

• PhD with 6+ years, MS with 9+ years, or BS with 11+ years of industry experience.
• Track record of strategic, creative, and effective advancement of preclinical drug discovery programs supported by robust data packages.
• Demonstrated experience independently developing and implementing robust, reproducible SAR-enabling assay cascades supporting drug discovery programs.
• Experience successfully managing a team directing and coaching employees.
• Experience participating in and/or leading cross-functional teams.
• Excellent verbal and written communication and interpersonal skills.
• Desire and capacity to participate in a dynamic and fast-paced research setting.
• Desire and capacity to work collaboratively as part of a multidisciplinary team.

Responsibilities

• Participate in and/or lead cross-functional teams to advance therapeutic candidates from early discovery to clinical development.
• Lead from the bench—develop and execute project-specific cellular assays to define target mechanism and pharmacodynamic markers.
• Design triaging strategies to support SAR advancement and refinement of target compound profiles.
• Generate and lead target nomination/identification/validation activities for molecular glue degraders.
• Anticipate changes in scientific, competitive, or regulatory landscape and adjust plans accordingly.
• Communicate scientific progress and risk assessments to project stakeholders.
• Mentor junior scientists and contribute to a culture of scientific rigor and collaboration.

Skills

Strategic leadership

Cross-functional collaboration

Excellent communication

Team leadership

Mentorship

Adaptive in fast-paced research

Education

PhD with 6+ years

MS with 9+ years

BS with 11+ years

Job description

Position Overview

Neomorph is seeking an experienced drug discovery biologist with extensive experience participating in or leading programs through strategic, intellectual, and experimental contributions. The role will be critically involved in supporting Neomorph's growing pipeline by driving advancement of programs from early discovery through IND-enabling studies. The successful applicant will proactively collaborate across line functions to establish overarching project strategies and advance programs towards data-driven go/no go decisions.

Key Responsibilities

• Participate in and/or lead cross-functional teams to advance therapeutic candidates from early discovery to clinical development through strategic prioritization, effective interdisciplinary collaboration, and efficient technical execution.
• Lead from the bench - independently lead the development and execution of project-specific cellular assays to define target mechanism of action, assess markers of pharmacodynamic response, and identify relevant patient populations.
• Design and implement effective triaging strategies to support SAR advancement and refinement of target compound profiles based on deep mechanistic understanding of underlying biology.
• Generate and lead new target nomination/identification/validation activities that leverage unique aspects of the molecular glue degrader modality.
• Anticipate, evaluate, and strategically respond to changes in scientific, competitive, or regulatory landscape.
• Effectively communicate scientific advancements, strategic shifts, and risk assessments to project stakeholders.
• Contribute to Neomorph's culture of scientific rigor, open collaboration, and continuous learning by openly sharing expertise and providing mentorship to junior scientists.

Required Qualifications

• PhD with 6+ years, MS with 9+ years, or BS with 11+ years of industry experience
• Track record of strategic, creative, and effective advancement of preclinical drug discovery programs supported by robust data packages
• Demonstrated experience independently developing and implementing robust, reproducible SAR-enabling assay cascades supporting drug discovery programs
• Experience successfully managing a team directing and coaching employees.
• Experience participating in and/or leading cross-functional teams
• Excellent verbal and written communication and interpersonal skills
• Desire and capacity to participate in a dynamic and fast-paced research setting
• Desire and capacity to work collaboratively as part of a multidisciplinary team

Preferred Qualifications

• Experience with targeted protein degradation
• Experience managing teams of one or more associate scientists

What we offer

• Industry competitive compensation
• Annual target bonus
• Stock options
• 401K plan
• Career advancement opportunities
• Monthly town halls to share business and scientific updates

Work Hard, Stay Well

• Comprehensive medical, dental, and vision plans for employees and their dependents
• Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
• Employee Assistance Program
• 10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
• Supplemental pay for Pregnancy Disability Leave
• Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care

Lifestyle

• Casual work environment
• Volunteer days off each year to spend time contributing to causes you care about
• Flexible work schedule
• Access to onsite gym
• Onsite space to store your bicycle (or surfboard)

Have Fun!

We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).

About Us

Neomorph is a venture backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against 'undruggable targets'. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment.

Neomorph is headquartered in San Diego, California.

Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state or local law.

Notice to Agencies

Neomorph will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Neomorph via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Neomorph. No fee will be paid in the event the candidate is hired by Neomorph as a result of the referral or through other means.