Associate Director, Pricing and Access Analytics

amylyx; Cambridge (MA); Remote; USD 150,000 - 210,000; Full time

Job summary

Amylyx is seeking an Associate Director, Pricing Strategy & Access Analytics to act as a hands-on partner within Market Access. You will lead pricing analyses, gross-to-net modeling, and contracting evaluations while shaping access strategies for avexitide pending FDA approval.

You will collaborate with Finance, Legal, and Commercial teams to align assumptions, monitor policy trends, and deliver actionable insights that support patient access. Remote-friendly in the United States.

Qualifications

• Bachelor's degree required; advanced degree preferred (MBA/MPH/MS/PharmD).
• 6+ years in market access, pricing, or related pharmaceutical/biotech roles.
• Strong understanding of U.S. pricing, GTN, payer, PBM, and reimbursement dynamics.
• Ability to build analytical models and communicate recommendations to stakeholders.
• Experience in rare disease or launch planning is a plus.

Responsibilities

• Lead pricing analysis, scenario planning, GTN modeling, and contracting economics.
• Develop dashboards and insights to inform pricing and access decisions.
• Collaborate cross-functionally to align pricing assumptions and ensure compliant decisions.
• Monitor policy trends and channel evolution affecting pricing and access.

Skills

Pricing strategy

Analytical modeling

Excel

PowerPoint

Payer negotiations

Education

Bachelor's degree

MBA or related preferred

Job description

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values - be audacious, be curious, be authentic, be engaged, and be accountable - creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine's toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

Amylyx is seeking an Associate Director, Pricing Strategy & Access Analytics to serve as a hands-on strategic partner within Market Access. Reporting to the Senior Director, Market Access Strategy, this individual will be responsible for helping lead pricing strategy, analytics, gross-to-net modeling, contracting evaluation, and related decision support. The role will also support broader market access priorities, including identifying actionable payer and PBM insights, monitoring coverage and channel strategy trends, and generating patient access analytics to inform decision-making. The role will translate complex access, pricing, and customer data into clear, actionable recommendations that support access to avexitide (subject to FDA approval) for patients with post-bariatric hypoglycemia (PBH), an area of significant unmet need.

Responsibilities

Pricing strategy and analytics:

Lead pricing analysis, scenario planning, gross-to-net modeling, rebate and contracting economics, competitive pricing assessments to inform avexitide launch price and lifecycle decisions.

Build and maintain financial models that evaluate pricing options, payer and PBM contracting opportunities, customer trade-offs, access implications, and business-case assumptions.

Partner with Sr. Director, Access Strategy and co-lead pricing committee with Market Access, Finance, Forecasting, Legal, Compliance, Commercial, and Analytics teams to align pricing assumptions, pressure-test recommendations, and support compliant decision-making. Helps maintain and operationalize pricing committee.

Monitor and analyze policy and pricing trends with potential to impact launch of avexitide

Partner with finance to help assess risk and develop mitigation solution for potential government pricing calculations and reporting

Ensure compliance and State Drug Pricing Transparency reporting.

Broader access analytics:

Analyze payer coverage, utilization management, formulary positioning, reimbursement dynamics, claims trends, abandonment, reversals, pull-through performance, and patient access barriers.

In collaboration with commercial operations and market access stakeholder, develop dashboards, scorecards, customer insights, and executive-ready materials that synthesize payer, PBM, health system, specialty pharmacy, channel, and patient services trends into actionable recommendations.

Monitor external market trends, policy changes, competitive dynamics, Medicare/Medicaid reimbursement considerations, and channel evolution that may affect pricing, access, and reimbursement strategy.

Support vendor selection and management for market access data, pricing analytics, and research projects, ensuring high-quality outputs and timely delivery.

Required Qualifications

Bachelor's degree required; advanced degree such as MBA, MPH, MS, PharmD, or related discipline preferred.

6+ years of experience in market access, pricing, contracting, analytics, finance, forecasting, patient services, or related pharmaceutical/biotech roles;

Strong understanding of U.S. pricing, gross-to-net, payer, PBM, health system, specialty pharmacy, reimbursement, and patient access dynamics.

Demonstrated ability to build analytical models, interpret complex data, and communicate practical recommendations to cross‑functional and senior stakeholders.

Experience in rare disease, specialty pharmacy, launch planning, pricing strategy, contracting analytics, or patient services analytics preferred.

Advanced Microsoft Excel, PowerPoint, pivot table, financial modeling, PBM/payer negotiations & scenario analysis skills

High business and P&L acumen, with a strong foundation of GTN accounting dynamics across access customer types (commercial, government, patient services, specialty pharmacy, trade & distribution)

High integrity, strong collaboration skills, and comfort operating in a fast‑paced, cross‑functional (???) environment.

Ability and willingness to travel occasionally

Work Location and Conditions

At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance covera