Associate Director, Outcomes Research

Tempus; United States; Remote; USD 150,000 - 210,000; Full time

Benefits offered by this job

Incentive compensation

Restricted stock units

Medical benefits

Job summary

Tempus, a leader in precision medicine, seeks an Associate Director to lead high-impact outcomes research for biopharma partners within its Data Business. You will design and execute retrospective HEOR/RWE studies, develop novel methods, and translate complex data into regulatory-grade insights to accelerate drug development.

You will guide a small team of outcomes research scientists, collaborate with Data Science, Biostatistics, and Product teams, and ensure rigorous adherence to GEP/HIPAA

Qualifications

• 7+ years in HEOR/RWE with leadership experience.
• Oncology expertise required.
• Experience with messy real-world data (EHR, claims, and genomic data).

Responsibilities

• Oversee end-to-end retrospective database analyses and study protocol design.
• Advise biopharma clients on innovative study designs and publications.
• Lead development of novel HEOR/RWE methodologies (e.g., ECA, causal inference).
• Publish in peer-reviewed venues and present at conferences.
• Collaborate with Data Science, Biostatistics, and Product teams to scale methods.

Skills

Outcomes research leadership

Clinical data interpretation

Cross-functional collaboration

Communication to biopharma executives

Regulatory/HIPAA awareness

Education

PhD (preferred) in Epidemiology/Biostatistics/Health Economics

MS/PharmD in related quantitative field

Masters in Epidemiology/Biostatistics/Health Economics

Tools

R

SAS

Job description

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. The Associate Director will lead high-impact outcomes research for Tempus’s biopharma partners, sitting at the intersection of traditional outcomes research and cutting-edge data science. This is a high-visibility, client-facing role within the Data Business. You won’t just apply existing frameworks; you will develop and validate novel epidemiological methods to unlock the full potential of Tempus’s multimodal datasets. The ideal candidate is a scientific visionary who can translate complex, non-linear data into regulatory-grade insights that accelerate drug development and improve patient outcomes.

Key Responsibilities

• Research Design & Implementation: Oversee the end-to-end execution of retrospective database analyses. You will act as the primary architect for study protocols, ensuring they push the boundaries of current HEOR/RWE standards while maintaining scientific rigor.
• Scientific Thought Leadership: Serve as a subject matter expert for biopharma clients, advising them on "first-in-kind" study designs. You are expected to contribute to the broader scientific community through high-impact publications and presentations at conferences like ISPOR, ISPE, and ASCO.
• Client Strategy & Partnership: Partner with Key Account Directors and Business Development to identify opportunities where novel methodology can solve "unsolvable" client problems (e.g., rare disease characterization or complex biomarker validation).
• Methodological Innovation: Lead the development of novel approaches for RWE, including the use of external control arms (ECA), causal inference in high-dimensional data, and the integration of longitudinal clinical data with molecular/genomic signatures.
• Scientific Thought Leadership & Publication Strategy: Drive the strategy and roadmap for scientific dissemination. Lead the authoring and publication of high-impact peer-reviewed manuscripts, abstracts, and conference presentations to demonstrate methodologic rigor and support broader healthcare evidence generation.
• Cross-Functional Partnership: Bridge the gap between Data Science, Biostatistics, and Product teams to productize successful novel methods, ensuring they are scalable across the Tempus ecosystem.
• Project Management & Quality: Ensure all innovative research meets stringent regulatory and ethical standards (e.g., GEP, HIPAA), delivering high-quality results on timelines that match the pace of the biopharma industry.
• People Management: Manage a small team of outcomes research scientists, providing hands‑on guidance on analytical projects and career development and growth.

Qualifications

• Education: PhD (preferred), PharmD, or Masters degree in Epidemiology, Biostatistics, Health Economics, or a related quantitative field.
• Experience: 7+ years in HEOR/RWE, with at least 3 years in a leadership capacity. Deep expertise in oncology is required.
• Methodological expertise: Proven track record of developing or implementing advanced analytical methods (e.g., target trial emulation, propensity score applications in complex cohorts, causal inference, or machine learning-augmented epidemiology) and creative problem solving.
• Technical Proficiency: Advanced skills in R or SAS. Experience working with "messy" real-world data (EHR, claims, and/or genomic data) is essential.
• The "Consultant" Mindset: Exceptional ability to walk into a room of biopharma executives and simplify complex methodological hurdles into a clear strategic roadmap.
• Leadership: Demonstrated experience managing junior scientists and leading cross-functional squads in a fast-paced, high-growth environment

Salary and Benefits

U.S. Pay Range: $150,000 - $210,000

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience.

• Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.