Associate Director job at Biogen in San Francisco, CA

Remote; San Francisco (CA); Hybrid; USD 161,000 - 222,000; Full time

Benefits offered by this job

Medical, dental, vision, and life

401(k) with company match

Employee stock purchase plan

Tuition reimbursement

Job summary

Biogen in San Francisco, CA seeks an Associate Director, Clinical Biomarkers Lead to drive biomarker strategies across immunology and neuromuscular programs. This management role blends hands-on leadership with cross-functional collaboration in a hybrid setting.

You will oversee biomarker development, mentor teams, and collaborate with research, clinical development, regulatory, and medical affairs to influence clinical execution and regulatory submissions.

Qualifications

• PhD with 10+ years industry experience.
• 4+ years direct experience leading biomarker strategies in immune-mediated diseases.
• Excellent communication and leadership in matrix environments.

Responsibilities

• Develop and implement comprehensive biomarker strategies for programs in clinical development.
• Drive generation, analysis, and interpretation of biomarker data in clinical studies.
• Mentor group focused on biomarker strategy development and implementation.
• Coordinate biomarker activities with research, regulatory, medical affairs and commercial teams.
• Oversee outsourced projects with CROs, technology partners, and academics.
• Support planning and execution of clinical trials; review protocols and regulatory filings.
• Collaborate with translational teams to analyze biomarker datasets.
• Engage regulators and industry via conferences and publications.

Skills

Biomarker leadership

Cross-functional collaboration

Immunology expertise

Data interpretation

Regulatory interactions

Communication

Mentorship

Education

PhD

Tools

Cytometry

Immunoassays

Job description

Associate Director, Clinical Biomarkers Lead

Location: San Francisco, California

Work Arrangement: Hybrid — 2–3 days per week in San Francisco; remote candidates may be considered

Employment Type: Full-time

Salary: $161,000–$221,750 annually + short- and long-term incentives

People Management: Matrix management and mentorship responsibilities; Management-level position

Experience: PhD with 10+ years of industry experience, including 4+ years directly leading and implementing clinical biomarker strategies in immune-mediated diseases

Education: PhD required

Job Level: Management

About This Role

We are seeking a highly motivated and experienced Associate Director, Clinical Biomarkers Lead to support clinical biomarker development activities for our portfolio of immunology and neuromuscular clinical programs. As the Associate Director, Clinical Biomarkers Lead, you will be responsible for the oversight of the development, implementation, and execution of biomarker strategies for programs across the Biogen portfolio. Reporting directly to the West Coast Hub Head of Clinical Biomarkers and as a key member of the development team, you will support end-to-end biomarker development for our novel therapeutic candidates.

While this position is ideally based in San Francisco, CA as a Hybrid model (2–3 days/week), we are open to considering remote candidates with the right experience and qualifications. The pay range posted encompasses the pay range for both potential work locations. Actual pay will be determined by the selected candidate’s work location, as well as relevant experience and qualifications.

What You'll Do

• Develop and implement comprehensive biomarker strategies for therapeutic programs in clinical development, including pivotal/Phase 3 programs.
• Drive the generation, analysis, and interpretation of biomarker data in clinical studies as a key member of cross-functional program teams.
• Provide guidance and mentorship to members of the group focused on biomarker strategy development and implementation.
• Liaise with relevant stakeholders in research, clinical development, regulatory, medical affairs and commercial to coordinate and align biomarker activities in support of immunology therapeutic programs.
• Build strong partnerships with external collaborators by identifying potential academic partners to accelerate achievement of biomarker goals and maintain existing sponsored research agreements.
• Matrix manage biomarker assay development scientists and oversee/manage multiple outsourced projects with contract research laboratories, technology partners, and academics.
• Support the planning and execution of clinical trials; author and/or provide senior review of clinical protocols, medical affairs, and regulatory documents/filings.
• Collaborate with immunology research, translational immunology, clinical research, biometrics, clinical pharmacology, and others to execute translational studies and analyze and interpret biomarker datasets.
• Actively engage with regulators and industry professionals via conference presentations, workshops, consortia, and publications to influence best practices for biomarker development and clinical implementation.

Who You Are

You are an experienced biomarker leader with a proven track record of developing and delivering biomarker strategies across all stages of drug development. You will have excellent strategic thinking, communication, and collaboration skills while being able to influence without authority and efficiently drive alignment amongst multiple stakeholders to efficiently progress therapeutic programs in clinical development.

Required Skills

• PhD with 10+ years industry experience.
• 4+ years direct experience leading/implementing clinical biomarker strategies in immune-mediated diseases including for late-stage/pivotal studies.
• Exceptional communication skills with proven ability to deliver clear, concise biomarker-focused data and presentations tailored to different audiences including commercial colleagues.
• Demonstrated leadership in biomarker sciences including authoring manuscripts, regulatory documents, and direct interactions with regulators.
• Strong understanding of the clinical development and life cycle management process.
• Well versed in relevant technologies, particularly cytometry and immunoassay technologies with strong understanding of inherent advantages and limitations specifically with respect to clinical implementation.
• Ability to quickly absorb new information and develop an understanding of the relevant biology, pathway, mechanism of action (MOA), and disease indication(s).
• Proven scientific leadership and matrix management of high-performing individuals and cross-functional teams required.
• Ability to prioritize and deploy resources effectively and appropriately to meet key goals and timelines.

Job Level

Management

Additional Information

Compensation

Base Compensation Range: $161,000–$221,750 annually

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills and experience, job location, and internal equity.

Regular employees are eligible to receive both short-term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

Benefits

• Medical, dental, vision, and life insurance
• Fitness and wellness programs, including a fitness reimbursement
• Short- and long-term disability insurance
• A minimum of 15 days of paid vacation and additional end-of-year shutdown time off (December 26–December 31)
• Up to 12 company-paid holidays plus 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid maternity and parental leave benefit
• 401(k) program participation with company-matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.