Associate Director/Director, Clinical Scientist

Expedition Therapeutics Inc.; San Francisco (CA); On-site; USD 180,000 - 240,000; Full time

Job summary

Expedition Therapeutics Inc. seeks an Associate Director/Director, Clinical Scientist to lead clinical development studies in COPD, Bronchiectasis, and Asthma.

You will partner with Clinical Operations, Biostatistics, Regulatory Affairs, and CMC to design, execute, and interpret trials that support global development and regulatory approval. The role requires hands-on protocol development, trial execution, and translating complex clinical data into actionable insights for cross-functional and

Qualifications

• Advanced degree or equivalent with substantial clinical development experience.
• Associate Director: 4+ years; Director: 5-7+ years of clinical research/clinical development experience.
• Experience in respiratory or related inflammatory therapeutic areas preferred.
• Experience authoring/reviewing protocols, ICFs, and CSR.
• Strong communication and collaboration with CROs and sites.
• Proven ability to operate strategically and execute in a fast-paced environment.

Responsibilities

• Serve as clinical science lead/co-lead for studies (Phase 1b/2/3) evaluating COPD, Bronchiectasis, and Asthma.
• Contribute to development plans, study protocols, and amendments with leadership.
• Authorship/review of protocols, ICFs, CRFs, SAPs, and study reports.
• Serve as contact for CROs, investigators, and clinical sites.
• Review and interpret trial data; support DMC, safety monitoring, and data cleaning.

Skills

Clinical trial leadership

Protocol development

Data interpretation

Regulatory liaison

Cross-functional collaboration

Scientific communication

Education

PhD in life sciences

MD/DO/PharmD equivalent

Tools

ICH-GCP knowledge

CRO/vendor management

Job description

Expedition Therapeutics Inc. is an innovative, science-driven biotechnology company focused on developing novel therapeutics for chronic and acute respiratory diseases, including Chronic Obstructive Pulmonary Disease (COPD), Bronchiectasis, and Asthma. Our team combines deep discovery and developmental expertise with a nimble, collaborative culture to advance differentiated programs from early research through late-stage clinical development and commercialization.

Position Summary

Reporting to the Head of Clinical Development, the Associate Director/Director, Clinical Scientist will provide scientific and operational leadership in support of clinical development studies for our novel respiratory pipeline, spanning COPD, Bronchiectasis, and Asthma. This individual will serve as a core scientific member of the clinical development team, partnering closely with Clinical Operations, Biostatistics, Regulatory Affairs, Clinical Pharmacology, and CMC to design, execute, and interpret clinical trials that support successful global development and regulatory approval.

The ideal candidate brings strong scientific and clinical trial expertise in respiratory or related inflammatory disease areas, a track record of hands-on contribution to protocol development and trial execution, and the ability to translate complex clinical data into clear, actionable insights for cross-functional and executive stakeholders. Level of hire (Associate Director vs. Director) will be commensurate with the selected candidate's experience.

Key Responsibilities

• Serve as clinical science lead/co-lead for one or more clinical studies (Phase 1b/2/3) evaluating novel treatments for COPD, Bronchiectasis, and/or Asthma.
• Contribute to the design and development of clinical development plans, study protocols, and protocol amendments in collaboration with the clinical and medical leadership team.
• Author and/or critically review key study documents, including protocols, informed consent forms, case report forms, statistical analysis plans, and clinical study reports.
• Serve as a primary scientific and clinical point of contact for CROs, investigators, and clinical sites throughout study start-up, conduct, and close-out.
• Review, interpret, and synthesize clinical, safety, and efficacy data during trial conduct; support data review committees, safety monitoring activities, and data cleaning efforts.
• Author or contribute to clinical sections of regulatory submissions (e.g., IND/CTA, briefing documents, NDA/MAA) and support responses to health authority information requests.
• Partner cross-functionally with Biostatistics, Clinical Pharmacology, Regulatory Affairs, Clinical Operations, Medical Affairs, and CMC to ensure scientific and operational alignment across development programs.
• Present clinical data, study status, and scientific updates to internal governance committees, as well as external stakeholders such as advisory boards, key opinion leaders, and scientific conferences.
• Maintain current knowledge of the respiratory disease landscape, competitive intelligence, and emerging science relevant to COPD, Bronchiectasis, and Asthma.
• Support the publication strategy, including abstracts, manuscripts, and scientific congress presentations.
• Contribute to training and mentorship of junior clinical development staff (Director level).

Qualifications

• Advanced degree (PhD, PharmD, MD, PA, NP, or equivalent) in a relevant scientific or clinical discipline; or an advanced clinical/nursing degree (e.g., RN, MSN) with substantial relevant experience.
• Associate Director: 4+ years, or Director: 5-7+ years, of clinical research/clinical development experience within biotech or pharmaceutical companies, including hands-on, trial-level clinical science responsibilities.
• Experience in respiratory, pulmonary, or related inflammatory therapeutic areas (COPD, Asthma, Bronchiectasis, or similar) strongly preferred.
• Demonstrated experience authoring and/or reviewing protocols, informed consent forms, clinical study reports, and other core clinical trial documents.
• Working knowledge of ICH-GCP and experience supporting global, multi-regional clinical trials.
• Strong analytical, written, and verbal communication skills, with the ability to translate complex clinical data into clear, actionable insights for varied audiences.
• Experience partnering effectively with CROs, central labs, and other clinical trial vendors.
• Proven ability to operate strategically and execute tactically in a fast-paced, collaborative, and entrepreneurial environment.

Why Join Us

• Opportunity to make a meaningful scientific contribution to novel therapies for patients living with COPD, Bronchiectasis, and Asthma.
• High-visibility role with direct influence on clinical development strategy and study execution.
• Collaborative, entrepreneurial culture built on a strong scientific foundation.
• Competitive compensation, equity participation, and a comprehensive benefits package.