Associate Director, Biostatistics (Late Stage Oncology)

Merck & Co.; Basking Ridge (NJ); On-site; USD 175,000 - 263,000; Full time

Job summary

Daiichi Sankyo, Inc. is seeking a senior statistician to lead complex studies, including design, SAP development, CSR input and regulatory interactions. The role guides CRO programmers, ensures data quality with the data manager, and contributes to regulatory submissions worldwide under some supervision.

The position emphasizes statistical leadership across development plans, vendor oversight, and collaboration with study teams to optimize study outcomes and timelines.

Qualifications

• Master's degree in statistics or biostatistics required.
• PhD in statistics or biostatistics preferred.
• 8+ years of relevant experience in the pharmaceutical industry with a master's degree.
• 5+ years of relevant experience in the pharmaceutical industry with a PhD preferred.

Responsibilities

• Lead statistical activities for complex studies including study design, protocol development, CRF review, SAP development, analysis files development, statistical analysis accuracy validation, results interpretation and CSR input and review.
• Act as main statistical contact for the assigned studies and projects.
• Provide guidance to study team on all aspects of statistical activities; collaborate with data manager to ensure high quality data.
• Contribute to Drug Development Strategy to ensure scientifically sound designs that meet regulatory requirements and deliver the predefined product profile.
• Review CRO/vendor proposals and budgets; set expectations on deliverables and timelines to guide CRO biostatisticians and programmers.

Skills

Statistical analysis

Study design

Regulatory submissions

Education

Master's degree in statistics or biostatistics

PhD in statistics or biostatistics

Job description

Job Summary

Position leads complex studies in study design, statistical analysis and interpretation of results with some supervision. This position contributes to specific aspects of drug development plans with minimal supervision and contributes to documents submitted to Health Authorities globally with some supervision. This position also guides contract research organization (CRO) programmers and statisticians in preparing analysis files and performing statistical analyses. Additionally, this position interacts with study teams, as well as statisticians and programmers at CROs. This position works under some supervision to solve complex study problems.

Responsibilities

• Protocol Development, Case Report Form (CRF; review), Statistical Analysis Plan (SAP), Statistical Analysis, Results Interpretation, and clinical study report (CSR):
• Leads statistical activities for complex studies including study design, protocol development, CRF review, SAP development, analysis files development, statistical analysis accuracy validation, results interpretation and CSR input and review.
• Acts as main statistical contact for the assigned studies and projects.
• Provides guidance to study team on all aspects of statistical activities; collaborates closely with data manager to ensure high quality data.
• Drug Development Strategy: Provides input to multiple aspects of the development plan to ensure the study designs at each phase of the development are scientifically sound, can fulfill regulatory requirements and deliver the pre-specified product profile.
• CRO / Vendor Oversight: Review CRO/vendor proposal and budget. Establishes procedures through regular interaction, setting expectation on deliverables and timelines to guide CRO biostatistician and statistical programmers on complex studies. Ensures deliverables are accurate and delivered according to the timelines.
• Global Health Authority Interaction / Negotiation: Contributes to documents submitted to Health Authorities globally by providing input for the interaction or by writing the interaction document. May participate in meeting or teleconferences with Health Authorities
• Global BDO Strategy to Improve Drug Development: Primarily participates and may occasionally lead moderately complex initiatives, with some level of supervision, to improve the harmonization and efficiency of drug development which leads to cost savings and shortened timelines for the company.

Education Qualifications

• Master's Degree in statistics or biostatistics required
• PhD in statistics or biostatistics preferred

Experience Qualifications

• 8+ years of relevant experience in the pharmaceutical industry with a masters degree required
• 5+ years of relevant experience in the pharmaceutical industry with a PhD preferred

Travel Requirements

Ability to travel up to 10% of the time.

Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.

Salary Range

USD$175,440.00 - USD$263,160.00

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