Associate Director - Antibody Discovery Programs

Alloy Therapeutics; Waltham (MA); On-site; USD 150,000 - 200,000; Full time

Benefits offered by this job

Unlimited PTO

Continuing education stipend

Wellness program & EAP

Job summary

Alloy Therapeutics in Waltham, MA seeks an Associate Director of Antibody Discovery Programs to lead multispecific antibody initiatives and oversee dozens of programs with pharma and biotech partners. You will drive strategy, evaluate data in real time, and mentor a cross-functional team to deliver impactful therapeutic discoveries.

This role requires strong communication across time zones, collaboration with external partners, and up to 10% travel.

Qualifications

• PhD in Biochemistry, Biotechnology, or Biology with 6+ years of industry experience in early drug discovery.

Responsibilities

• Provide scientific oversight of multispecific antibody discovery programs and drive strategy with partners.
• Evaluate data in real time and adjust strategies to ensure successful therapeutic discovery campaigns.
• Lead cross-functional teams, collaborate with project leaders, and ensure timely delivery of project milestones.

Skills

Leadership

Communication

Project management

Team mentoring

Global collaboration

Education

PhD in Biochemistry/Biotechnology/Biology

Master's with 10+ years experience

Tools

Yeast-display

Antibody engineering

Job description

Role Location: Waltham, MA

The Company

We are Alloy Therapeutics— a biotechnology ecosystem and Product Development Organization (PDO) empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. May the Best Drug Win.

Alloy has evolved from a startup into a global product development organization operating 11 divisions across 5 research sites in 4 countries on 3 continents. Our model - Integrated Independence - combines centralized capabilities with entrepreneurial operating divisions. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture.

At Alloy, we have an ethos of "Mentorship-By-Apprenticeship" in all of our positions. We stride to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations to appreciate their colleagues who have less flexibility. We are all one team!

About the Role at Alloy Therapeutics

As Associate Director of Antibody Discovery Programs, you will play a key role in shaping and leading strategies for our antibody discovery initiatives. This position entails driving the discovery of novel antibody-based therapeutics, with special focus on multispecific antibodies. You will be accountable for scientific oversight of dozens of therapeutic programs every year by working collaboratively with a range of large pharma companies, emerging biotech companies and academic collaborators.

A crucial aspect of this role involves providing a deep understanding of drug discovery projects to drive effective project strategies in collaboration with our partners. You will ensure executional excellence by evaluating scientific strategies, reviewing data in real time and making the necessary scientific adjustments to ensure a successful therapeutic discovery campaign. In addition, you will collaborate closely with project leaders overseeing the successful completion of project activities, accomplishing shared objectives, and meeting rigorous partner timelines. Another key accountability of this role is serving as a change agent to drive continuous improvement of ADS service offerings to achieve sustained operational efficiency.

Strong communication skills are essential for this role, as you will interact with a diverse group of stakeholders both within and outside the company. You will also be accountable for high quality partner communication throughout the project life cycles, including drafting research proposals, updating project status and timelines, and presenting final deliveries. In parallel, you will provide regular project updates and presentations to internal stakeholders to ensure alignment with project goals and timelines and addressing any potential issues or concerns promptly.

This role will report directly to the site head Antibody-Powered Division Waltham, MA, with autonomy owning various stakeholders, projects, and tasks in a dynamic start-up environment while keeping up the pace of Alloy.

How You’ll Drive Impact

• Drive: Scientific direction and execution of multispecific antibody projects.
• Innovate: Ensure the application of cutting‑edge technologies and methodologies in antibody discovery projects.
• Collaborate: Integrate protein engineering and cutting‑edge efforts efficiently into product offerings and engage with external collaborators in discovery of biologics.
• Deliver: Efficient execution of partner projects balancing quality, timelines, and costs, while ensuring successful completion of therapeutic discovery that meet our partners’ objectives.
• Lead: Marshall, inspire, and mentor a cross‑functional team of scientists. Lead by example by going the extra mile to ensure we are successful delivering on projects.
• Communicate: Communicate effectively with key stakeholders externally and internally, fostering productive interactions both upward and downward, and across teams at different sites.

Key Responsibilities

• Accountable for scientific success of antibody discovery and multispecific engineering campaigns.
• Drive major decisions, balance tradeoffs and resolve technical issues with a campaign.
• Coordinate execution and partner relationship with alliance management and project management.
• Lead process improvement initiatives across ADS functional areas.Bring innovative scientific and technological solutions to increase business competitiveness.

Qualifications

• You have a PhD in a relevant scientific field (e.g. Biochemistry, Biotechnology, Biology) with a minimum of 6 years of industry experience in early drug discovery and development, or a master’s degree with 10+ years of relevant industry experience.
• You have broad and deep experience with antibody discovery and engineering, especially yeast‑display based methods.
• You have a strong background in the design and optimization of antibody‑based therapeutics.
• You have a proven track record of successful execution and delivery of projects within scope, budget, and timeline.
• You have demonstrated the ability to work in a fast‑paced, dynamic environment and adapt to changing priorities and deadlines.
• You have excellent communication skills, both written and verbal, with the ability to effectively communicate with stakeholders at all levels.
• You have excellent leadership and team management skills, with the ability to motivate and mentor team members.
• Ability to work across various US and international time zones.
• Accommodate occasional travel as needed (10%).

Taking Care of Our People

We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you’re single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.

Compensation

• Competitive base and equity compensation commensurate with level of experience and independence
• 401(k) company match

Health & Family

• Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered
• Company‑paid disability (STD, LTD) and life insurance
• Paid parental leave
• Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval)

Unique Perks

• Unlimited PTO (paid time off) and flexible schedules
• Annual stipend for continuing education with commitment to your career through individualized professional development plan
• Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness

Pay Transparency
At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated range is $150,000 - $200,000, with the final offer based on factors like your experience, skills, and alignment with our needs.

Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines.

We are proud to offer competitive compensation and benefits, aiming to support our team’s professional and personal well-being. If you have any questions about pay or benefits, we’re here to help.

Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [e-mail]. We will make every effort to respond to your request for disability assistance as soon as possible.