API Process Engineer: Technical Operations

Biopharma Careers; Elkton (KY); On-site; USD 87,000 - 137,000; Full time

Job summary

Merck & Co. in the United States is seeking a Process Engineer, Technical Operations – Drug Substance to join our growing team.

This role provides technical support for API manufacturing, technology transfers, and process optimization within a fast-paced small‑molecule site. You will collaborate across Manufacturing, Quality, Engineering, and R&D to ensure cGMP compliance, robustness, and efficient campaigns.

Qualifications

• Degree in Chemical Engineering, Chemistry, or related discipline.
• Typically 2–5+ years’ API manufacturing or process development experience.
• Exposure to API processing, scale‑up, and cGMP expectations.

Responsibilities

• Provide technical support for API manufacturing processes, including chemical synthesis, purification, crystallization, and drying.
• Support capital projects, commissioning, qualification, technology transfer, and validation activities.
• Analyze process data, monitor performance, and drive continuous improvement.
• Collaborate with Manufacturing, Quality, Engineering, Supply Chain, and R&D teams.
• Ensure compliance with cGMP, safety, and environmental standards.

Skills

Chemical Engineering

API manufacturing

Process development

cGMP knowledge

Cross-functional collaboration

Education

Bachelor's degree in Chemical Engineering or related

Job description

Merck & Co. in the United States is seeking a Process Engineer, Technical Operations – Drug Substance to join our growing team.

This role provides technical support for API manufacturing, technology transfers, and process optimization within a fast-paced small‑molecule site. You will collaborate across Manufacturing, Quality, Engineering, and R&D to ensure cGMP compliance, robustness, and efficient campaigns.