Analytical Scientist, Large Molecule

Elanco; Indianapolis (IN); Hybride; USD 120 000 - 180 000; Plein temps

Avantages offerts par ce poste

Paid Time Off

401(k) matching

Parental leave

Relocation support

Employee Resource Groups (ERGs)

Résumé du poste

Elanco, a global animal health leader, seeks an Analytical Scientist – Large Molecule to drive development, validation, and transfer of chromatographic and LC/MS methods for biologics. You will partner across discovery, bioprocess, formulation, and quality teams to ensure robust, compliant analytical capabilities.

You will mentor junior scientists, maintain ELN documentation, and contribute to regulatory submissions while upholding data integrity and quality standards at global sites and

Qualifications

• Bachelor’s degree required in a relevant science (analytical chemistry, biochemistry, biophysics, chemical engineering, or related).
• Minimum 5+ years of hands-on experience in biotechnology/biopharmaceuticals focusing on large-molecule characterization.
• Proven track record developing/validating HPLC/UPLC, electrophoretic, and LC/MS methods for biologics.

Responsabilités

• Design, develop, and optimize chromatographic, electrophoretic, and LC/MS methods for proteins and vaccines.
• Lead method validation, verification, qualification, and tech transfer across sites and CRO/CDMO partners.
• Ensure data integrity and compliance with GMP/regulatory expectations in all workflows.

Connaissances

Large molecule characterization

HPLC/UPLC

LC/MS

Electrophoresis

Data integrity

Scientific communication

Formation

Bachelor’s Degree in Analytical Chemistry, Biochemistry, Biophysics, Chemical Engineering, or related

Outils

ELN platforms

Chromatography data systems (Empower)

Description du poste

At Elanco (NYSE: ELAN) – it all starts with animals! As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose – all to Go Beyond for Animals, Customers, Society and Our People. At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you’ll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.

Your Role

As an Analytical Scientist – Large Molecule, you will be an integral part of Elanco’s R&D organization, driving the development, optimization, and implementation of chromatographic, electrophoretic, and mass spectrometry (LC/MS) analytical methods for biopharmaceutical products. In this role, you will advance state-of-the-art analytical techniques for therapeutic proteins and vaccines, support bioprocess development, and lead method validation, qualification, and transfer efforts across global internal manufacturing sites and external CRO/CDMO partners.

Your Responsibilities

Method Development & Optimization: Design, develop, and optimize robust chromatographic (e.g., SEC, RP-HPLC, IEX, HIC), electrophoretic (e.g., CE-SDS, icIEF), and LC/MS (including intact mass and peptide mapping) analytical methods for therapeutic protein and vaccine candidates.

Innovate and implement analytical solutions to support diverse drug formulations, stability studies, and upstream/downstream bioprocess development.

Method Validation, Transfer & Compliance: Lead analytical method validation, verification, qualification, and technical transfer activities across global Elanco sites and contract research/manufacturing organizations (CROs/CDMOs).

Ensure all analytical methods, protocols, and documentation adhere strictly to data integrity standards and GMP/regulatory expectations.

Mentorship & Cross-Functional Collaboration: Train, guide, and mentor junior scientists and technical associates to ensure technical consistency and high-quality analytical practices across the organization.

Serve as the analytical subject matter expert on interdisciplinary project teams, collaborating closely with Discovery Research, Bioprocess Development, Formulation, and Quality teams.

Data Integrity & Technical Documentation: Author and review comprehensive technical reports, method standard operating procedures (SOPs), validation protocols, and regulatory submission summaries.

Maintain meticulous Electronic Lab Notebook (ELN) documentation and uphold the highest laboratory safety and quality standards.

What You Need to Succeed (Basic Qualifications)

• Education: Bachelor’s Degree (B.S.) in Analytical Chemistry, Biochemistry, Biophysics, Chemical Engineering, or a related scientific discipline .
• Experience: Minimum of 5+ years of relevant hands-on experience in the biotechnology or biopharmaceutical industry focused on large-molecule characterization .
• Core Technical Expertise: Demonstrated track record developing and validating HPLC/UPLC-based, electrophoretic, and LC/MS analytical methods for biologics .
• Communication & Problem Solving: Strong scientific problem-solving abilities coupled with excellent written and verbal communication skills .

What Will Give You a Competitive Edge (Additional Preferences)

• Direct experience characterizing recombinant proteins, monoclonal antibodies (mAbs), oligonucleotides, and therapeutic peptides .
• Practical experience leading method validation, qualification, and transfer within a cGMP-regulated environment .
• Proficiency with Design of Experiments (DoE), statistical analysis, and statistical software packages (e.g., JMP).
• Hands‑on experience working with Electronic Laboratory Notebook (ELN) platforms and chromatography data systems (e.g., Empower).
• Demonstrated ability to independently design, prioritize, and execute complex scientific studies while navigating evolving project priorities .
• Prior background or familiarity with the Animal Health regulatory framework (USDA/FDA) is a plus .

Work Environment & Travel Requirements

Work Location: Global Elanco Headquarters – Greenfield, IN . Work Arrangement: Hybrid (laboratory-based presence with flexible office work arrangements) . Travel: Up to 10% annual domestic or international travel as needed for technical site visits and cross-site transfers .

Inclusion & Diversity Note

Don’t meet every single requirement? Studies have shown underrepresented groups are less likely to apply to jobs unless they meet every single qualification. At Elanco, we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!

Elanco Benefits and Perks

• Paid Time Off: Competitive PTO plus two week-long company-wide US shutdowns (Summer & Year-End) .
• Retirement & Savings: Up to 6% 401(k) company matching and annual performance bonus eligibility .
• Family Support: 8-week fully paid parental leave and flexible work arrangements .
• Relocation Support: Multiple relocation packages available for eligible candidates .
• Community & Culture: Access to 9 active global Employee Resource Groups (ERGs) fostering diversity, equity, and belonging .

Equal Opportunity Employer & Compliance

Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.

Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job‑related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.

Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.

Elanco Animal Health Incorporated (NYSE: ELAN) is a global leader in animal health dedicated to innovating and delivering products and services to prevent and treat disease in farm animals and pets, creating value for farmers, pet owners, veterinarians, stakeholders, and society as a whole. With nearly 70 years of animal health heritage, we are committed to helping our customers improve the health of animals in their care, while also making a meaningful impact on our local and global communities. At Elanco, we are driven by our vision of Food and Companionship Enriching life and our Elanco Healthy Purpose™ CSR framework – all to advance the health of animals, people and the planet. Learn more at www.elanco.com.