Analytical Data Science Lead (Director)

F. Hoffmann-La Roche AG; Boston (MA); On-site; USD 152,000 - 283,000; Full time

Job summary

Genentech, a member of the Roche group, is seeking an Analytical Data Science leader to oversee programming and analytical strategy across multiple molecules in clinical development. You will mentor a global team and partner with data management and regulatory groups to deliver impact.

The role champions R workflows, Python and SAS, scalable automation, and AI initiatives from concept to delivery, with emphasis on CDISC SDTM/ADaM and end‑to‑end data workflows in a regulatory context.

Qualifications

• 12+ years of statistical and analytical programming in clinical development.
• Deep expertise in CDISC SDTM/ADaM standards.
• Advanced proficiency in R, Python, and SAS.
• Experience leading remote/global teams and cross-functional partnerships.

Responsibilities

• Oversee programming and analytical strategy across multiple molecules in clinical development.
• Mentor and grow a high‑performing global team.
• Drive adoption of advanced R workflows and scalable automation.
• Lead high‑impact AI initiatives and regulatory engagements.
• Partner with Data Management and external vendors to ensure pipeline integration.

Skills

Team leadership

Statistical programming

R

Python

SAS

CDISC SDTM/ADaM

Regulatory submissions

Communication skills

Education

Master’s or PhD in Statistics/Biostatistics/CS/Life Sciences

Tools

R workflows

SAS

Python

Job description

Opportunity

The Opportunity Analytical Data Science is a core function within Product Development Data Sciences that provides strategic leadership and scientific rigor across clinical development. Our teams generate data-driven insights, identify opportunities for scale, and implement impactful solutions across our global portfolio.

Strategic Leadership:

Oversee programming and analytical strategy across multiple molecules or disease areas, aligning with clinical, regulatory, and enterprise data goals.

Team & People Leadership:

Manage, mentor, and build a high-performing global team, defining your own leadership philosophy to foster technical excellence, continuous growth, and remote collaboration.

Technical & R Innovation:

Drive the adoption of advanced R workflows, open-source tools, Python, and scalable automation, serving as a champion for expanding modern data science practices across the team.

AI & Advanced Analytics:

Lead high-impact AI initiatives and exploratory visualization tools from problem definition to execution, driving measurable value for clinical development.

Cross-Functional & Vendor Oversight:

Act as a strategic partner to cross-functional stakeholders (such as Data Management) and manage external vendor delivery to ensure seamless pipeline integration.

Regulatory & Industry Influence:

Represent the data science function in global regulatory engagements and contribute to industry conferences or publications to advance programming standards.

Who You Are

You are an inspiring technical and people leader who thrives in navigating complexity, fostering innovation, and driving strategic data science functions forward. You have an advanced degree (Master’s or PhD) in Statistics, Biostatistics, Computer Science, Life Sciences, or a related quantitative field.

You have 12+ years of experience in statistical and analytical programming within clinical development, with demonstrated impact across multiple programs or regulatory submissions.

You have deep expertise in clinical trial data standards (e.g., CDISC SDTM/ADaM), along with advanced proficiency in R (developing custom workflows/tools) and SAS or Python.

You have proven experience leading direct reports in a global, matrixed, or remote environment, with a track record of driving team adoption of new tools and methodologies.

You have proven ability to lead impactful AI/digital initiatives and shape broader organizational data strategies.

You have strong communication skills with experience presenting at industry conferences, contributing to publications, or engaging with health authorities.

You bring deep expertise in clinical trial data standards (e.g., CDISC SDTM and ADaM), regulatory submission requirements, and end-to-end data workflows.

Preferred Qualifications

You have a proven track record of peer-reviewed publications and industry conference contributions.

You have experience leading programming strategy for global regulatory submissions, including integrated summaries (ISS/ISE).

You have familiarity with metadata-driven programming approaches or enterprise-level data standardization.

You have a proven ability to drive functional innovation through automation, process improvement, or adoption of emerging tools.

You have exposure to real-world data or digital health integration within clinical development.

You have participated in industry working groups, consortia, or recognized contributions to advancing programming standards or practices.

Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of Massachusetts is $152,300.00 - $282,800.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. The next step is yours.