Analytical Chemist

Eli Lilly and Company; Indianapolis (IN); On-site; USD 65,000 - 169,000; Full time

Benefits offered by this job

Company bonus

Comprehensive benefits package

Job summary

Lilly in Indianapolis, IN is seeking an analytical chemist to join the Synthetic Molecule Design and Development team. This hands-on role (>70% bench work) focuses on developing analytical methods and characterizing chemical processes to advance drug candidates from early development through manufacturing readiness.

You will apply chromatography (HPLC, GC, NMR) and MS techniques, work with chemists and engineers, and translate analytical data into actionable insights while upholding safety and

Qualifications

• Bachelor or Master of Science in Analytical Chemistry, Biochemistry, Chemistry, or a related field.
• Experience with chromatographic method development or validation in pharmaceutical, chemical, or regulated industry.
• Authorized to work in the United States on a full-time basis; Lilly will not sponsor visas.

Responsibilities

• Develop and optimize analytical methods to measure purity, potency, and other quality attributes of small molecule drug substances and intermediates.
• Select and implement analytical techniques (HPLC, GC, NMR, MS) to support chemical process development and transfer methods to GMP labs.
• Assess stability of development materials under stressed conditions to evaluate potential degradation.
• Collaborate with synthetic chemists and process engineers to ensure methods guide development and manufacturing testing.
• Perform laboratory activities with safety and technical rigor, adhering to policies.
• Identify new concepts, solve problems, and contribute across multiple projects.
• Communicate results clearly to represent technical and business implications.

Skills

Analytical chemistry

Chromatographic method development

Problem solving

Team collaboration

Safety discipline

Education

Bachelor's or Master's in Analytical Chemistry/Related

Tools

HPLC

GC

NMR

MS

Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life‑changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Overview

Synthetic Molecule Design and Development have an exciting opportunity for an analytical chemist to join our development group. In this hands‑on laboratory role (>70% bench work), you will develop analytical methods and characterize chemical processes to advance drug candidates from early development through manufacturing readiness. You will expand and apply your expertise in chromatographic method development and leverage complementary techniques (mass spectrometry, NMR) while partnering closely with synthetic chemists and process engineers to solve critical process development challenges. The ideal candidate brings practical chromatography experience, strong problem‑solving skills, and the ability to translate analytical data into actionable insights for project teams.

Position Responsibilities

• Develop and optimize analytical methods to accurately measure purity, potency, and other critical quality attributes of small molecule drug substances and synthetic intermediates.
• Select and implement appropriate analytical techniques (HPLC, GC, NMR, MS) to support chemical process development—independently generating data that elucidates reaction mechanisms, characterizes kinetic behavior, and identifies process‑related impurities.
• Assess stability of development materials under stressed conditions to evaluate potential degradation using chromatographic techniques.
• Collaborate with synthetic chemists and process engineers to ensure analytical methods are suitable for guiding development activities and can be successfully transferred to GMP laboratories for routine testing and manufacturing support.
• Perform laboratory activities with a strong emphasis on safety and technical rigor, while adhering to local policies and procedures.
• Identify and apply new scientific concepts, exhibit strong problem‑solving skills, and be self‑motivated to contribute across multiple projects.
• Demonstrate strong written and verbal communication skills to represent both the technical aspects and business‑related implications of your work.

Basic Qualifications

• Bachelor or Master of Science degree in Analytical Chemistry, Biochemistry, Chemistry, or a related field.
• Experience with chromatographic (LC, GC, IC) method development or validation in pharmaceutical, chemical, or regulated industry setting
• Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F‑1 CPT, F‑1 OPT, F‑1 STEM OPT, J‑1, H‑1B, TN, O‑1, E‑3, H‑1B1, or L‑1.

Additional Skills/Preferences

• Working knowledge of mass spectrometry (LC‑MS, GC‑MS) and NMR spectroscopy
• Familiarity with chemical process development, synthetic organic chemistry, and rationales for establishing material specifications and testing plans.
• Experience troubleshooting and maintaining analytical instrumentation.
• Demonstration of scientific leadership and the ability to influence others.
• Ability to balance multiple responsibilities, prioritize activities, and navigate ambiguity.

Additional Information

• Travel: 0 to 10%
• Potential exposure to chemicals, allergens, and loud noises
• Lilly is an EEO/Affirmative Action Employer and does not discriminate based on race, gender, protected veteran status, disability, or any other legally protected status
• Position Local: Onsite Monday through Friday, Indianapolis, IN; Lilly Technology Center‑North (LTC‑N)

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 - $169,400

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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