6-Month AI-Driven Translational PK/TK Co-op

MSD Malaysia; Boston (MA); Hybrid; USD 39,000 - 111,000; Full time

Job summary

Merck & Co., Inc. in Rahway, NJ, USA is offering a 6‑month co‑op in Translational Sciences and Outsourcing within the PDMB department.

The role focuses on AI-enabled exposure prediction for preclinical PK/TK data, combining data curation, modeling, and scientific communication to support DMPK and NDS decisions with limited in vivo data. The project emphasizes structure-aware modeling, rigorous benchmarking, and collaboration across Data Science, PKPD, and toxicology teams.

Qualifications

• Pursuing a Master’s or Ph.D. in data science, computer science, applied mathematics, statistics, computational chemistry, or related field.
• Experience in machine learning, statistical modeling, scientific computing, or computational modeling.

Responsibilities

• Curate and quality-check preclinical cross-dose PK/TK datasets with provenance and holdout splits.
• Conduct TK analysis with exposure endpoints (AUC, Cmax) across compounds, doses, and routes.
• Develop and benchmark AI-enabled and hybrid models against baselines.
• Evaluate model performance and uncertainty estimation for nonlinear PK behaviors.
• Create visualizations and presentations for cross-functional stakeholders.
• Share project results through internal/external publications.

Skills

Python

NumPy

pandas

scikit-learn

PyTorch

JAX

model evaluation

reproducible workflows

Education

Master’s or Ph.D. in data science or related quantitative field

Tools

KNIME

SciPy

Job description

Merck & Co., Inc. in Rahway, NJ, USA is offering a 6‑month co‑op in Translational Sciences and Outsourcing within the PDMB department.

The role focuses on AI-enabled exposure prediction for preclinical PK/TK data, combining data curation, modeling, and scientific communication to support DMPK and NDS decisions with limited in vivo data. The project emphasizes structure-aware modeling, rigorous benchmarking, and collaboration across Data Science, PKPD, and toxicology teams.