Senior Scientist (Chemistry)

BIOCHROMATOGRAPHIX INTERNATIONAL PTE. LTD.; Singapore; On-site; SGD 75,000 - 95,000; Full time

Job summary

A biotechnology startup in Singapore is seeking a Senior Scientist for Chemistry to develop new ligand chemistries for purification of biological materials. This role involves hands-on development and manufacturing activities in the lab, alongside responsibilities like planning experiments, optimizing ligands, and preparing patents. The ideal candidate will have a PhD in chemistry and at least three years of lab experience. Strong communication and organizational skills are essential. This position offers a unique opportunity to advance innovative biotechnological solutions.

Qualifications

• Minimum of three years industrial laboratory experience with solid supports.
• Experience in conjugation and reaction optimization is preferred.
• Ability to work collaboratively in a team-oriented environment.

Responsibilities

• Plan and conduct laboratory activities for chromatography media development.
• Modify solid supports such as polymethylmethacrylate and cellulose.
• Develop and optimize conjugation reactions and quantify sites modified.

Skills

Laboratory techniques

Communication skills

Organizational skills

Team collaboration

Education

PhD degree in a relevant field of chemistry

Tools

oqPCR

ELISA

flow cytometry

SDS-PAGE

Western Blot

Job description

BioChromatographix is a startup company developing novel chromatography media for purification of viruses and other biological materials. We seek a Senior Scientist for Chemistry to develop new ligand chemistries and optimize binding of ligands to our polymeric matrices. We are looking for hands on development and manufacturing at our Singapore laboratory.

Responsibilities

The Scientist is responsible for planning and conducting laboratory activities related to development of chromatography media, including

• Modifying solid supports, such as polymethylmethacrylate, cellulose and silicon
• Identifying appropriate ligands
• Developing and optimizing conjugation reactions
• Quantifying sites modified
• Planning experiments and writing protocols
• Conducting experiments to confirm performance of chromatography media
• Analyzing samples
• Writing reports and documenting experimental results
• Conducting literature searches including freedom to operate searches of existing patent literature
• Preparing patents

Supporting chromatography applications, including

• Conducting application studies, preparing protocols, conducting experimental work and writing reports
• Writing Application Notes and White Papers
• Preparing publications for submission to journals

Other technical related assignments may be required.

Background

The successful candidate will meet the following requirements.

• A PhD degree in a relevant field of chemistry
• A minimum of three years industrial laboratory experience with solid supports
• Experience in the following analysis techniques:
  oqPCR, ELISA, flow cytometry
  oSDS-PAGE and Western Blot
• Experience in proper scientific method, including the use of controls, DOE, and analysis of results
• Experience in conjugation and reaction optimization is preferred
• Superior skills in spoken and written communication is required
• Excellent organisational skills and attention to detail.
• Ability to work collaboratively in a team-oriented environment