Senior Product Engineer (Mechanical)

Illumina; Singapore; On-site; SGD 120,000 - 180,000; Full time

Benefits offered by this job

ERG programs

Equal opportunity employer

Job summary

Illumina is seeking a Manufacturing/Mechanical Engineer to support product lifecycle from design to mass production. You will lead product transfer, perform data analysis, and apply DOE/FMEA to optimize quality and cost. Expect cross-functional collaboration and mentorship for junior staff.

Expertise in GD&T, DFMA, thermodynamics, CAD/PLM, and data analytics will drive process improvements across sites and ensure robust, reliable products.

Qualifications

• Minimum 5 years related experience or 3 years with Master’s/PhD.
• Deep expertise in mechanical design, GD&T, and DFMA.
• Strong thermodynamics, heat transfer, optics, and fluidics knowledge.
• Proficient CAD and PLM; data analytics with Excel, Minitab, JMP.

Responsibilities

• Lead product transfer readiness for manufacturing and NPI.
• Perform data trending, DOE, and FMEA to optimize quality and costs.
• Control change processes (ECR/CRs) and validate tests.
• Mentor junior engineers and collaborate across sites.

Skills

GD&T

Tolerance analysis

DFMA

Thermodynamics

Heat transfer

Optics & fluidics interface

CAD

PLM systems

Data analytics (Excel, Minitab, JMP)

Scripting (VBA/Python)

Education

Bachelor’s degree

Master’s degree

PhD (with experience)

Tools

CAD

PLM

Minitab

JMP

Excel

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Position Summary

Responsible for supporting product lifecycle activities, including new product introduction, product transfer, and ongoing manufacturing operations. This role ensures product quality, yield, and compliance through engineering evaluation, troubleshooting, and continuous improvement initiatives. Collaborates cross-functionally to drive process enhancements, cost optimization, and operational excellence, enabling smooth transition from design to production and sustaining high-performance standards throughout the product lifecycle.

Position Responsibilities

Common Responsibilities

• Support and drive product transfer into manufacturing.
• Perform data trending and analysis.
• Apply FMEA, DOE, and statistical analysis to optimize product quality and reduce costs.
• Drive process improvements, cost reduction, and product sustaining activities.
• Manage Engineering Change Request and Notifications (CRs and CNs), including updates to work instructions and test requirements.
• Support documentation: engineering drawings, BOMs, test reports, assembly procedures, and validation plans.
• Participate in continuous improvement initiatives and operational excellence programs.
• Frequent cross-functional collaboration and occasional travel to other sites.
• Provide guidance and mentorship to junior staff.

Mechanical Engineering Design & Development

• Architect subsystem changes (enclosure/chassis, mechanisms, thermal/fluidics/optical interfaces).
• Conduct advanced analyses (FEA-lite, thermal modeling, fluidic characterization).
• Define reliability test plans (ALT/HALT, life testing); own acceptance criteria.

Manufacturing Support & NPI

• Lead readiness for mass production: PFMEA updates, process controls, test method validation (TMV).
• Approve critical fixture design changes; ensure calibration strategies.

Quality, Reliability & Data

• Institutionalize SPC dashboards and paretos; own CTQ monitoring.
• Lead troubleshooting using structured frameworks (8D, KT) with statistical validation.
• Define CTQs and monitor Cp/Cpk for critical features.
• Mentor juniors on interpreting SPC and DOE outputs.
• Frames decisions with confidence intervals and risk quantification.
• Coaches team to replace “gut feel” with evidence.
• Escalates issues with quantified impact (yield %, cost).

Project & Process

• Create and maintain integrated schedules; present status/risks at core team.
• Manage cross-functional action logs; drive risk registers (severity × occurrence × detectability).

Documentation & Compliance

• Author/approve validation protocols and reports; ensure full traceability.
• Ensure change control rigor (ECR, deviations, waivers); audit readiness.

Collaboration

• Coordinate design engineering and operations; harmonize requirements with service feedback.
• Travel to CM/supplier sites for first builds; lead lessons learned.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Position Requirements

• Typically requires a minimum of 5 years of related experience with a Bachelor’s degree; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience.
• Deep expertise in mechanical mechanisms, GD&T, tolerance analysis and DFMA principles.
• Strong understanding of thermodynamics and heat-transfer fundamentals.
• Familiarity with optics and fluidics interface considerations in complex systems.
• Advanced proficiency in CAD and PLM systems.
• Skilled in data analytics tools such as Excel, Minitab and JMP; scripting experience (e.g., VBA/Python) is a plus.
• Familiarity with ISO 13485, IEC 61010 and design control frameworks.
• Proven ability to mentor and guide junior engineers on technical approaches and best practices.
• Strong ability to communicate technical information clearly, concisely, and in a stakeholder-oriented manner.
• Proven capability to anticipate manufacturability challenges and design for robustness and reliability.
• Proven ability to evaluate technical trade-offs (COGS, quality, schedule) using data-driven decision-making.
• Experience coaching engineers on analysis depth, documentation quality, and disciplined execution.

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission.

Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics.

We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race.

We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [e-mail].

To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf.

The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity. We are made up of dedicated professionals, all-in on creating a better world - and we need every skill set on our path to making genomics useful for all.

Learn more about life at Illumina.