Senior Computational Chemist – AI-Driven Drug Discovery

A*STAR Research; Singapore; Vor Ort; SGD 45.000 - 65.000; Vollzeit

Zusammenfassung

The A*STAR Research unit in Singapore is seeking a junior computational chemist to advance AI-enabled approaches for small molecule drug discovery. You will apply cutting-edge computational methods to drive hit-to-lead design and lead optimization.

Candidates should have a life sciences or computational sciences background with 2+ years of related experience, strong scripting skills (Python), and familiarity with industry tools such as Schrödinger, Desmond, or Knime.

Qualifikationen

• Undergraduate or master’s degree in life sciences or computational sciences with at least 2 years of related work experience.
• Good knowledge in chemistry and protein structure with basic medicinal chemistry.
• Experience using computational chemistry software (Schrödinger, Desmond, Knime) in drug discovery.
• Experience developing ML models for drug discovery applications.
• Publications in the field are a plus.
• Fluent in at least one scripting language (e.g., Python).
• Independent, creative, collaborative, and strong communication skills.

Aufgaben

• Apply computational chemistry and AI-enabled methods to small molecule drug discovery projects.
• Collaborate with biologists and chemists for hit-to-lead design and lead optimization.
• Work with AI scientists and software engineers to develop ML models for in-house programs.

Kenntnisse

Python

molecular modeling

machine learning

team collaboration

Ausbildung

Bachelor's or Master's degree in life sciences or computational sciences

Tools

Schrodinger

Desmond

Knime

Jobbeschreibung

The A*STAR Research unit in Singapore is seeking a junior computational chemist to advance AI-enabled approaches for small molecule drug discovery. You will apply cutting-edge computational methods to drive hit-to-lead design and lead optimization.

Candidates should have a life sciences or computational sciences background with 2+ years of related experience, strong scripting skills (Python), and familiarity with industry tools such as Schrödinger, Desmond, or Knime.