Scientist/Senior, Biotherapeutics Development (BTI)

A*STAR RESEARCH ENTITIES; Singapore; On-site; SGD 70,000 - 90,000; Full time

Job summary

A leading research institution in Singapore is seeking a highly motivated Scientist to join their Biotherapeutics Development group. The successful candidate will contribute to developing biotherapeutics aimed at clinical applications. Responsibilities include characterising monoclonal antibodies, conducting in vivo studies, and mentoring. The ideal candidate has a PhD in Biomedical Science or related fields and practical experience in molecular biology techniques. This role offers the opportunity to collaborate with industry partners and advance innovative research.

Qualifications

• PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines.
• Familiar with the requirements for selecting potential lead and hit candidates.
• Strong interest in translational and applied research aspects.

Responsibilities

• Characterise and evaluate monoclonal antibodies and their efficacy.
• Contribute to the therapeutics development pipeline.
• Conduct in vivo studies including immunisations and xenograft models.

Skills

Cell culture

Immunology

Data analysis

Flow cytometry

Communication skills

Organisational skills

Education

PhD in Biomedical Science

Tools

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Bioassays

Job description

Job Description:

We are seeking a highly motivated Scientist to join our Biotherapeutics Development group. The successful candidate will contribute to research activities developing biotherapeutics with a goal towards clinical applications and commercialisation.

Key responsibilities include:

• Characterise and evaluate monoclonal antibodies (mAbs), its antigen target and mechanism of action needed for a pre-clinical dossier
• Contribute to therapeutics development pipeline through hit and lead identification
• Conduct in vivo studies, such as immunisations and tumour xenograft models
• Work in project teams with internal and external collaborators
• Contribute to mentorship of students and interns
• Prepare presentation slides, reports, technology disclosures, grant proposals
• Maintain accurate and timely experimental records
• Support routine lab operations, including procurement, equipment maintenance, lab safety compliance, and general housekeeping

Job Requirement:

• A PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines
• Familiar with the requirements needed for selection of potential lead and hit candidates
• A strong interest in the translational and applied aspects of research, including collaborations with industry partners.
• Practical experience in cellular and molecular biology (such as cell culture, flow cytometry, western blot, ELISA, immunoprecipitation, mammalian cell transfection, immunohistochemistry, bioassays, and data analysis) and in vivo studies
• Strong organisational and communication skills
• Able to work independently and collaboratively in a team

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.