Scientist II

Abbvie; Singapore; On-site; SGD 120,000 - 180,000; Full time

Job summary

Requirements include a BSc with 7+ years or MSc with 5+ years in biology/biochemistry/engineering, strong scientific writing, and cross-functional collaboration. Equal opportunity employer and safety-focused culture are highlighted.

Qualifications

• BSc with 7+ years or MSc with 5+ years in relevant field.
• Excellent written/oral communication of research or regulatory materials.
• Experience supporting late-stage biologics manufacturing and tech transfer.

Responsibilities

• Resolve key project hurdles in late-stage/commercial biologics manufacturing and tech transfer.
• Support/troubleshoot current commercial manufacturing operations.
• Lead/assist tech transfer and scale-up validations for new products.
• Support CMC lifecycle management and post-approval validation.
• Collaborate with process development on late-stage transfers and validation.
• Investigate non-conformances; identify root causes; provide scientific recommendations.
• Author/review CMC submissions; support inspections and audits.
• Represent MSAT antibody group in CMC program teams; maintain relationships.
• Adhere to corporate standards, safety, and GxP.

Skills

Scientific writing

Cross-functional communication

Tech transfer

Process validation

Education

Bachelor/Master in Biology, Biochemistry, Chemical or Biochemical Engineering

Job description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Job Description

Purpose:

Technical expert who independently investigates, identifies, develops, and optimizes new methods/techniques for critical project needs, to support both laboratory and commercial manufacturing processes. Apply scientific/engineering principles and statistical process design/analysis to develop robust antibody manufacturing processes. Act as lead scientist, critically evaluate scientific/regulatory advances, and integrate into R&D programs. Support manufacturing, process validation, regulatory submission, and continuous improvement for late-stage and commercial manufacturing of ADCs. Requires in-depth knowledge of late-phase process transfer, process validation, process improvements. Strong cross-functional communication needed.

Major Responsibilities:

1. Resolve key project hurdles using technical expertise; support late-stage/commercial biologics manufacturing, tech transfer, process validation, investigations, troubleshooting, scale-up, continuous improvement
2. Work in dynamic/diverse team to support & troubleshoot current commercial manufacturing
3. Support/lead new product introduction at AbbVie sites or third-party manufacturers; ensure successful tech transfer, scale-up, validation
4. Support CMC life-cycle management and post-approval continued process validation for commercial antibody processes
5. Collaborate with process development on late-stage tech transfers, scale-up, and validation during transition to commercial manufacturing
6. Support product investigations/non-conformances; identify root causes; make scientific/quality recommendations
7. Author/review CMC sections of submissions; support agency inspections, inquiries, audits
8. Represent MSAT antibody group in CMC program teams; maintain strong internal/external relationships
9. Adhere to corporate standards (code of conduct, safety, GxP, controlled substances, animal care where applicable)

Qualifications

B.Sc. + 7+ years, OR M.Sc. + 5+ years relevant experience
Field: Biology, Biochemistry, Chemical or Biochemical Engineering, or related fields
Effective writer/communicator of research or regulatory materials

Additional Information

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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