Manufacturing Systems Engineer (PLC)

Amgen; Singapore; On-site; SGD 70,000 - 110,000; Full time

Job summary

Amgen Singapore is seeking a Manufacturing Systems Engineer I (PLC) to join our engineering team. The role focuses on day-to-day automation support, troubleshooting, and improvements to maintain GMP-compliant manufacturing systems.

You will collaborate with multiple functions to enhance system reliability and operational performance. Ideal candidates bring a Bachelor’s degree in engineering and 2+ years of manufacturing automation experience, with hands-on work on Siemens and Rockwell PLCs,

Qualifications

• Bachelor’s degree in engineering or related field.
• 2+ years of related experience in manufacturing automation.
• Experience with GMP/GEP and regulatory expectations is a plus.

Responsibilities

• Provide day-to-day automation support, troubleshooting, incident investigation, and change implementation.
• Collaborate with cross-functional stakeholders to improve system reliability and regulatory compliance.
• Assist in validation, documentation, and handover for automation projects.

Skills

Automation troubleshooting

Cross-functional collaboration

GMP compliance

Documentation

Education

Bachelor’s degree in Engineering

Diploma in Engineering

Tools

Siemens PLCs

Rockwell PLC/HMI

SCADA systems

SQL Database

Job description

Career Category Engineering Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Manufacturing Systems Engineer I (PLC)

What you will do

• You approved implementations within assigned scope, resolve moderate-complexity issues, and collaborate with cross-functional stakeholders to improve system reliability, operational performance, and compliance with GMP, Good Engineering Practice (GEP), EHSS, and regulatory requirements.
• Provide day-to-day automation support, including troubleshooting, incident investigation, system monitoring, change implementation, and coordination with relevant stakeholders.
• Escalate and work closely with the Senior Manufacturing System Engineer on complex, high-impact, or non-routine issues.
• Assess, implement, test, deploy, and document automation changes in accordance with applicable SOPs and GMP requirements.
• Participate in technical discussions and provide technical assessment and advice within their assigned scope; engage the Senior Automation Engineer for complex, high-impact, or non-routine changes.
• Support technical work and small-to-medium automation projects from design and risk assessment through commissioning, qualification, startup, and handover.
• Troubleshoot and investigate automation issues; prepare technical reports; implement technical solutions and CAPA actions; and identify recurring issues for improvement.
• Escalate complex issues to the Senior Automation Engineer.
• Identify, develop and implement continuous improvement opportunities to improve automation-system reliability, efficiency and compliance.
• Monitor and analyze established metrics; recommend and implement approved improvements.
• Promote Safety, Quality and Compliance culture and continuous improvement mindset that lead to plant safety, quality and compliance to regulatory requirement
• Support audits and inspections and participate in discussions within their assigned technical scope.
• Prepare and review technical specifications, test plans, change records, implementation plans, contingency measures, and as-built documentation.
• Coordinate with Manufacturing, Quality, Maintenance, Process Engineering, IT/OT, EHSS and external service providers to execute operational activities, changes and technical issue resolution.
• Share technical knowledge and provide day-to-day guidance to junior engineers and contractors within their area of expertise.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

What we expect of you

• We are all different, yet we all use our unique contributions to serve patients.
• Master’s degree OR Bachelor’s degree and 2 years of directly related experience OR Associate’s degree and/or 4 years of directly related experience OR High school diploma / GED and 6 years of directly related experience
• Preferred 4+ years’ experience in manufacturing automation, particularly in biotechnology or pharmaceutical industries
• Preferred 4+ years' experience supporting and maintaining Siemens PLCs, DDCs, Building Management Systems (BMS), and Quality Environmental Monitoring Systems (QEMS) in a manufacturing or industrial environment.
• Working knowledge of Rockwell and Siemens PLC/HMI hardware, lifecycle management, control logic, HMI/SCADA systems, Microsoft SQL Database, industrial networks, field instrumentation, and environmental monitoring equipment.
• Experience troubleshooting system faults, assessing operational impact, and coordinating corrective actions with Operations, Maintenance, Engineering, Quality, and external service providers.
• Experience with utility skid equipment such as HVAC, Cooling Tower, Chiller, RO, Clean Steam and Waste Treatment system.
• Experience applying GMP requirements, including change control, risk assessment, testing, documentation, data integrity, computerized system validation, industrial standard (21 CFR Part 11, GAMP) and deviation or CAPA support.
• Experience supporting or delivering automation projects involving BMS, Siemens PLCs, or QEMS, from requirements and design through testing, commissioning, handover, and documentation.
• Strong communication, planning, and collaboration skills.
• Working knowledge of EHSS requirements

Your selection for this role will be subject to fulfilling the medical requirements of this job scope. If so, you will be informed of the medical check(s) that you may need to undergo. All medical related expenses incurred from this medical check shall be borne by the company.

What you can expect of us

• In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

For more information, visit www.amgen.com and follow us on www.twitter.com/amgen