Clinical Lead, Partnership

A*STAR Research; Singapore; On-site; SGD 120,000 - 160,000; Full time

Job summary

A leading research organization in Singapore is looking for a Clinical Lead to guide clinical strategy and direction for diagnostic product development. This role involves engaging with multi-stakeholder partnerships to ensure diagnostic solutions are clinically relevant and fully aligned with regulatory requirements. Candidates should possess a PhD or MD, with at least 10 years of clinical leadership experience. Strong communication skills and a proven ability to drive clinical initiatives in diagnostics are essential for success.

Qualifications

• Minimum 10 years’ experience in a clinical leadership role within diagnostics or pharmaceuticals.
• Experience in design and development of companion diagnostics.
• Strong professional relationships with key opinion leaders in clinical areas.

Responsibilities

• Lead clinical input and strategy across diagnostic development programs.
• Engage with partners to define clinical performance specifications.
• Advise on clinical study design and regulatory submissions.

Skills

Clinical leadership

Stakeholder management

Communication skills

Clinical strategy

Education

PhD in Clinical Sciences or related biomedical field or Medical Degree (MD/MBBS)

Job description

The Clinical Lead will play a pivotal role in guiding the clinical strategy and direction for diagnostic product development programs driven by multi-stakeholder partnerships. This role bridges clinical insight with product innovation, ensuring that diagnostic solutions emerging from collaborative programs are clinically relevant, evidence-based, and aligned with global regulatory and guideline requirements.

Key Responsibilities

• Lead the clinical input and strategy across partnered diagnostic development programs, from early concept to validation and implementation.
• Lead scoping and identification of companion diagnostics partnership opportunities, as well as partnership engagement with biotech and pharma companies.
• Engage with clinical, academic, and industry partners to identify unmet clinical needs and translate these into Target Product Profiles (TPPs) and clinical performance specifications.
• Review, interpret, and integrate relevant clinical guidelines (e.g., disease-specific, diagnostic, or screening guidelines) to define use cases and clinical utility frameworks.
• Advise on clinical study design, endpoints, and patient selection criteria to support product development and regulatory submissions.
• Coach and mentor internal teams—including partnership, tech teams, QA/RA—to ensure alignment between clinical strategy, product requirements, and partnership goals.
• Contribute to regulatory and ethics submissions related to diagnostic validation and clinical performance studies.
• Represent the organization in external meetings, working groups, and consortium activities that advance diagnostic development and clinical adoption pathways.

Requirements

• PhD in Clinical Sciences, Medicine, or related biomedical field or a Medical Degree (MD/MBBS) from a recognized university.
• Minimum 10 years’ experience in a clinical leadership role within a diagnostics or pharmaceutical development environment.
• Demonstrated ability to translate clinical insights into actionable product development specifications.
• Experience in design and development of companion diagnostics.
• Deep understanding and experience in diagnostic development lifecycles, including analytical and clinical performance evaluation, clinical validation studies, and evidence generation.
• Practical knowledge of international clinical and regulatory frameworks governing diagnostic products (e.g., HSA, FDA, IVDR, NMPA).
• Excellent communication and stakeholder management skills with experience engaging clinicians, researchers, regulators, and industry partners.
• Experience leading clinical programs in genomics, molecular diagnostics, or infectious disease testing.
• Familiar with health economics, clinical utility studies, or clinical implementation pathways.
• Proven record of contributing to cross-sector partnerships or consortium-based R&D initiatives.
• Strategic thinker with the ability to translate clinical knowledge into business growth and impact.
• Strong leadership and team-building skills with the ability to inspire and guide a diverse team of medtech professionals.
• Excellent communication and presentation skills, with the ability to effectively convey complex medical information to diverse stakeholders.
• Strong professional relationships with key opinion leaders practicing in key clinical areas including cancers, metabolic diseases, infectious diseases, mental health and population health in Singapore and globally.
• Business acumen and strategic thinking to drive the DxD Hub's clinical initiatives.