CIP Engineer (Clean-in-Place) - Engineering & CQV

Hyde Engineering + Consulting, Inc.; Singapore; Hybrid; SGD 120,000 - 180,000; Full time

Job summary

Hyde Engineering + Consulting, Inc. is seeking a CIP Engineer to design, commission, qualify, validate, and optimize CIP systems in Singapore pharma facilities.

The role blends engineering and CQV to ensure systems meet cGMP, FDA, EU GMP Annex 1, ISPE, and internal standards while supporting CQV from Concept Design through CPV. Requirements include 5–10 years in pharma/CQV, 3+ years CIP experience, and strong skills in P&ID review, validation planning, and technical reporting.

Qualifications

• Bachelor’s degree in engineering related to pharma manufacturing.
• 5–10 years of pharma or biopharmaceutical engineering and CQV experience.
• Minimum 3 years direct CIP engineering and qualification experience.
• Experience with GMP regulated facilities including biologics, vaccines, sterile manufacturing, and OSDis.
• Proven CQV protocol execution and validation documentation experience.

Responsibilities

• Review CIP system designs for pharma/biopharma facilities and support design reviews.
• Evaluate P&IDs, process flows, equipment layouts, and automation sequences for CIP.
• Support FAT, SAT and vendor package reviews and resolve design gaps.
• Develop and execute CQV activities: CTPs, IQ, OQ, PQ, validation reports.
• Coordinate cleaning validation strategy, sampling, and data analysis.
• Review CIP automation logic and sequence of operations.

Education

Chemical Engineering

Mechanical Engineering

Bioprocess Engineering

Process Engineering

Pharmaceutical Engineering

Related Engineering Discipline

Tools

P&ID review

FAT/SAT execution

Technical report writing

GMP regulations

Job description

Back CIP Engineer (Clean-in-Place) - Engineering & CQV

Engineering Tuas Contract Aug 4, 2026

Position: CIP Engineer (Clean-in-Place) - Engineering & CQV

Location: Singapore

The CIP Engineer will be responsible for the design review, commissioning, qualification, validation, optimization, and lifecycle management of Clean-in-Place (CIP) systems within pharmaceutical, biopharmaceutical, vaccine, API, and sterile manufacturing facilities. The role requires a combination of engineering expertise and CQV experience to ensure that CIP systems are designed, installed, tested, and operated in compliance with cGMP, FDA, EU GMP Annex 1, ISPE, and company quality standards. The successful candidate will support project execution from Concept Design through Operational Qualification (OQ), Performance Qualification (PQ), and Continued Process Verification (CPV).

Responsibilities

Engineering Responsibilities

• Review and support the design of CIP systems for pharmaceutical and biopharmaceutical manufacturing facilities.
• Evaluate P&IDs, process flow diagrams, equipment layouts, and automation sequences related to CIP systems.
• Verify CIP system design against process requirements, product contact surfaces, cleanability, and regulatory expectations.
• Support FAT, SAT, and vendor package reviews.
• Conduct engineering assessments for:
  • CIP skids
  • Process vessels and tanks
  • Bioreactors and fermenters
  • Transfer lines and manifolds
  • Fill-finish equipment
  • WFI and purified water interfaces
• Perform hydraulic and process evaluations to ensure adequate flow, velocity, turbulence, and coverage.
• Identify opportunities for CIP cycle optimization to reduce water, chemical consumption, and cycle times.
• Support troubleshooting of CIP failures and cleaning effectiveness issues.

CQV Responsibilities

• Develop and execute Commissioning and Qualification activities for CIP systems.
• Prepare and execute:
  • Commissioning Test Plans (CTPs)
  • Installation Qualification (IQ)
  • Operational Qualification (OQ)
  • Performance Qualification (PQ)
  • Validation Protocols
  • Validation Summary Reports (VSRs)
• Support traceability matrix development and management.
• Coordinate punch-list resolution and CQV documentation closure.

Cleaning Validation Responsibilities

• Support cleaning validation strategy development.
• Define worst-case product selection and cleaning validation matrices.
• Coordinate sampling activities including:
  • Swab sampling
  • Rinse sampling
• Analyze cleaning validation data and support final reports.
• Collaborate with Manufacturing, QA, QC, and Validation teams during execution.

Automation & Controls Support

• Review CIP automation logic and sequence of operations.

Qualifications and other requirements

Education

• Bachelor's Degree in:
  • Chemical Engineering
  • Mechanical Engineering
  • Bioprocess Engineering
  • Process Engineering
  • Pharmaceutical Engineering
  • Related Engineering Discipline

Experience

• 5-10 years of experience in pharmaceutical or biopharmaceutical engineering and CQV.
• Minimum 3 years of direct CIP engineering and qualification experience.
• Experience supporting GMP regulated facilities including:
  • Biologics
  • Vaccines
  • Sterile Manufacturing
  • OSD
  • API Facilities
• Proven experience executing CQV protocols and validation documentation.

Technical Skills

• CIP system design and operation
• Cleaning validation principles
• Commissioning and Qualification
• GMP regulations
• P&ID review
• FAT/SAT execution
• Technical report writing

Key Competencies

• Technical Leadership
• Problem Solving
• Project Execution
• Cross-Functional Collaboration
• Risk Assessment
• Documentation Excellence
• Communication and Stakeholder Management
• Attention to Detail
• Continuous Improvement Mindset

Success Measures

• The CIP Engineer will be considered successful when:
  • CIP systems are delivered, commissioned, and qualified on schedule.
  • Cleaning validation programs pass regulatory and internal quality audits.
  • CQV documentation is completed error-free and on time.
• CIP cycle performance meets defined operational and process requirements