Senior/ Principal Scientist - Peptide parenteral formulation development

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The Position

At Roche, we have an exciting opportunity for an expert in peptide parenteral formulation. You will work on multiple innovative projects with cutting-edge technologies that will have a meaningful impact on millions of lives.

As a Principal Scientist in Pharmaceutical Development, you will be part of the Department “Pharmaceutical Development” in Pharma Technical Development (PTD) in Basel, Switzerland. The department is responsible for developing parenteral drug products (Synthetic molecules and Biologics) from Phase 1 through Launch, including formulation and manufacturing process development, transfer to commercial manufacturing sites, and line extension development.

The Opportunity

Your major responsibilities include:

• Driving the pharmaceutical development of cutting-edge peptide parenteral formulations, from clinical development to market launch, including line extensions.
• Developing robust manufacturing processes for liquid and lyophilized peptide and small molecule formulations, overseeing scale-up, process characterization & validation, and transfer to global manufacturing sites.
• Acting as Pharmaceutical Project Leader in global CMC teams, cross-functional initiatives, and international committees, shaping regulatory submissions for all phases and market approvals, impacting patient access to medicines.

Who you are

You hold a Ph.D. or Master’s degree in chemistry, chemical/process engineering, or related fields, with at least 6 years of industry experience in formulation and process development of parenteral drug products for peptides.

• Proven experience authoring drug product sections of NDAs for peptide products and expertise in developing and launching peptides as parenteral combination products.
• Strong expertise in chemistry, solid-state characterization, and related fields.
• Experience with peptide analytical techniques, aseptic manufacturing, scale-up, tech transfers, and regulatory requirements.
• Experience in writing/reviewing regulatory CMC documents and evaluating program and submission risks from formulation and manufacturing perspectives.
• Excellent communication, stakeholder management, and collaborative skills, with a global mindset.

If you are an expert in peptide formulations and enjoy driving innovation, we would love to hear from you.

Who we are

Driven by a healthier future, over 100,000 Roche employees worldwide are dedicated to advancing science and ensuring access to healthcare. We have treated over 26 million people and conducted more than 30 billion diagnostics tests. We foster creativity, explore new possibilities, and aim to deliver life-changing healthcare solutions globally.

Let’s build a healthier future, together.