Postdoctoral position in Rab14-dependent trafficking

Introduction

UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL encourages excellence, individual recognition and responsibility.

Presentation

A postdoctoral position is available in the laboratory of Christian Widmann at the Department of Biomedical Sciences (DSB) of the University of Lausanne. Our group investigates the molecular and cellular mechanisms underlying the uptake of cell-penetrating peptides (CPPs) and physiological proteins carrying CPP sequences, such as homeoproteins.
We have recently uncovered a new endocytic pathway relying on the Rab14 protein (https://www.cell.com/action/showPdf?pii=S2211-1247%2821%2901418-2). A major focus of our research is now to characterize the Rab14-dependent trafficking pathway and to determine how these molecules escape from endosomes when endocytosis is used as the entry route. Our recent findings and ongoing projects provide exciting opportunities for the successful candidate to contribute to our understanding of these fundamental cellular processes.

Job information

Expected start date in position : August 2025

Contract length : A one-year contract with the possibility of extension depending on funding and performance

Activity rate : 100%

Workplace : Department of Biomedical Sciences - Rue du Bugnon 7 1005 Lausanne

Your responsibilities

The newly hired postdoctoral collaborator will use advanced cellular, biochemical, and imaging techniques to study the intracellular trafficking of CPPs and related proteins. She/he will be involved in experimental design, data analysis, and the development of new methodologies to monitor endosomal escape and intracellular delivery. The candidate will also have the opportunity to collaborate within a dynamic and interdisciplinary research environment.

Your qualifications

We are seeking a motivated and skilled postdoctoral researcher with:
• A PhD in life sciences or a related field
• Strong experience in cell biology, molecular biology, and biochemistry
• Hands-on expertise in cell culture, microscopy, and/or protein trafficking studies
• A background in membrane biology, endocytosis, or intracellular trafficking is highly desirable
• Excellent organizational and communication skills
• The ability to work independently and as part of a collaborative team

What the position offers you

• An exciting research project in a dynamic, internationally recognized laboratory
• A stimulating and collaborative environment within the DSB and the broader University of Lausanne
• Access to state-of-the-art facilities and multidisciplinary expertise
• A one-year contract with the possibility of extension depending on funding and performance

Contact for further information

Prof. Christian Widmann

Department of Biomedical Sciences

University of Lausanne

Email: E-Mail schreiben

For further information, please visit: https://wp.unil.ch/widmannlab/

Your application

How to Apply
Please submit your application by July 1st, 2025, including:
• A motivation letter
• Curriculum vitae
• A brief description of your research experience and doctoral thesis
• The names and contact details of three academic references

Please, send your full application in Word or PDF.
Only applications through this website will be taken into account.

We thank you for your understanding.

Additional information

UNIL is committed to:
• equality, diversity and inclusion within its community;
• ensuring an open and respectful environment that is conducive to personal development;
• offering working conditions that facilitate work-life balance;
• supporting early career researchers.

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