Principal Engineer – MSAT (Large Molecule Drug Product)

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R&D Talent Matchmaker | Connecting Innovators in Life Sciences Across the UK, EU & US | Senior Consultant and Key Account Manager at BioTalent

Candidates can be based 3 days per week in: Beerse (BE) | Cork (IE) | Leiden (NL) | Schaffhausen or Zug (CH)

Are you a seasoned MSAT or Technical Operations expert ready to take ownership of global large molecule projects? We're partnering with a leading biopharmaceutical company that pioneers monoclonal antibody innovation and brings life-changing medicines to patients worldwide.

As a Principal Engineer (Technical Owner), you will play a strategic, global role, serving as the technical voice within the product’s Value Chain Team (VCT) and leading complex, cross-functional projects from concept to delivery.

What You’ll Do

• Act as the Technical Owner for commercialized Drug Product (DP) large molecules.
• Represent MSAT in the Value Chain Team, shaping lifecycle and supply strategies.
• Drive technical leadership for process performance, risk assessments, and cost optimizations.
• Lead and coordinate product-related technical activities across internal and external manufacturing.
• Contribute to platform standardization, innovation projects, and new platform integration.
• Actively support failure investigations, validation processes, and process improvements.

What We’re Looking For

• 9+ years in a relevant technical/MSAT/GMP manufacturing role (6+ with MSc/PhD).
• Strong background in Drug Product development, lifecycle management, and process validation.
• Experience in global matrix organizations, with exceptional influencing and leadership skills.
• Fluent English; experience navigating multi-cultural, international teams.
• Proficiency with digital tools such as SAP, TruVault, TrackWise, MS Project, and statistical software like Minitab.

Why This Role?

You’ll report directly to a global supply chain leader with a track record in driving innovation and excellence across continents. You’ll be given the autonomy to shape technical strategies that truly impact global product delivery. Work with a company that is setting the standard for large molecule biopharma innovation.

Interested in hearing more (confidentially)?

Apply now or reach out via direct message for a conversation.

Seniority level

Mid-Senior level

Employment type

Full-time

Job function

Supply Chain, Science, and Research

Industries

Pharmaceutical Manufacturing, Biotechnology Research, and Manufacturing