Post-doctoral researcher - Call for applications Assistant Professor No. 14/2026/SN

Institute of Bioorganic Chemistry Polish Academy of Sciences; Polska; On-site; PLN 79,000 - 94,000; Full time

Job summary

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk poszukuje postdoka w Dziekanacie Nauk o RNA, który zajmie się charakterystyką ncRNA, circRNA i miRNA oraz ich rolą w mózgu i przysadce. Praca obejmuje profiling, analizy RNA-seq i scRNA-seq, oraz izolację kompleksów RNA-białko.

Wymagane jest PhD w biologii lub pokrewnym, doświadczenie w technikach biochemicznych i pracy z myszy, a także kompetencje w języku angielskim.

Qualifications

• Doktorat w biologii, biotechnologii lub pokrewionej dziedzinie.
• Publikacje w WoS (z pierwszym autorem) i prezentacje na konferencjach.
• Doświadczenie w biochemii i molekularnej biolologii oraz pracy z myszy.

Responsibilities

• Prowadzenie badań nad ncRNA, circRNA i miRNA w mózgu i przysadce.
• Profiling circRNA/miRNA oraz analizy ekspresji genów po perturbacjach ncRNA (RNA-seq, scRNA-seq).
• Izolacja i charakteryzacja kompleksów RNA-białko oraz RNA pull-down / RIP.
• Analiza danych omicznych (transkryptomicznych, proteomicznych).
• Współpraca z zespołem oraz mentorowanie młodszych pracowników.

Skills

Non-coding RNA biology

Mice handling

RNA techniques

Cell biology methods

English proficiency

Education

PhD in biology / related field

Tools

RNA-seq

RNA pull-down

RNA immunoprecipitation

FISH

BaseScope

immunofluorescence

Job description

Institute of Bioorganic Chemistry Polish Academy of Sciences

Organisation/Company Institute of Bioorganic Chemistry Polish Academy of Sciences Department Department of Non-coding RNAs Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 20 Nov 2026 - 23:59 (Europe/Brussels) Country Poland Type of Contract Temporary Job Status Full-time Hours Per Week 40 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Reference Number 14/2026/SN Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Research scope: Characterization of non-coding RNAs (ncRNAs), particularly circular RNAs (circRNAs) and microRNAs (miRNAs), and their functions in the brain, its isolated structures, and the pituitary gland.

The position is intended for researchers holding a PhD or higher degree, with expertise in non-coding RNA biology and conducting research using mouse models, particularly in the context of the nervous and/or neuroendocrine systems.

The work will involve conducting advanced research focused on elucidating the mechanisms of action of circRNAs and microRNAs in the brain and the pituitary gland. The research will include profiling of circRNA and miRNA, gene expression analysis following ncRNA perturbation with RNA sequencing (RNA-seq) and single-cell RNA sequencing, as well as the isolation and characterization of macromolecular complexes in which these ncRNAs are present.

The Institute of Bioorganic Chemistry of the Polish Academy of Sciences (ICHB PAS) is one of Poland’s leading research institutions, conducting scientific research in chemistry, molecular biology, bioinformatics, and biomedicine. The Institute provides access to state-of-the-art research equipment and advanced technological facilities.

I. Requirements for the candidates:

• A PhD degree (or equivalent) in biology, molecular biology, biotechnology, biochemistry or a related discipline.
• Documented research output in the form of research papers published in recognized scientific journals (found in the Web of Science database, including those with first authorship), and presentations at conferences.
• Experience in biochemistry and molecular biology techniques, including nucleic acid and protein isolation and quality control (QC), RT-qPCR, Western blotting, Northern blotting, RNA-seq, RNA pull-down, and RNA immunoprecipitation, as well as in cell biology methods, including FISH, fluorescence and confocal microscopy.
• Documented experience in working with laboratory animals (mice), together with the certificates to perform procedures on animals and collect organs.
• Proficiency in spoken and written English.
• Motivation to pursue further scientific development, including obtaining research funding through national and international competitive grant applications.
• Strong interpersonal skills, including good communication skills and the ability to work effectively as part of a team.
• The following will be considered an additional advantage: documented experience in the acquisition and analysis of high-throughput omics data, proficiency in optimizing advanced analytical protocols, and a proven track record of securing research funding through competitive grant applications.

1.Tissue collection and preparation: Preparation of mouse brain and pituitary gland tissues, followed by microdissection of specific brain regions, including the cerebral cortex, hippocampus, cerebellum, hypothalamus, and choroid plexus. Cryopreservation and cryostat sectioning of tissues for further analyses. Preparation of single-cell suspensions from tissues.

2. Transcriptomic and proteomic profiling: Collection and preparation of biological samples for RNA-seq, single-cell RNA sequencing (scRNA-seq), and miRNA profiling using NanoString technology or small RNA sequencing. Preparation of protein fractions for proteomic analysis by mass spectrometry.

3. Analysis of molecular interactions: Isolation and characterization of RNA-protein and circRNA-miRNA complexes using RNA pull-down and RNA immunoprecipitation techniques. In situ detection and imaging of proteins and RNA in tissue sections using RNAscope, BaseScope, and immunofluorescence.

4. Omics data analysis: Analysis and interpretation of high-throughput data, including transcriptomic and proteomic datasets.

5. Collaboration: Close collaboration with the research team within the Department and external partners, as well as providing scientific guidance and support to junior researchers.

6. Reporting and publications: acquiring, processing and interpretation of the results, data management, preparation of internal reports and manuscripts, and presentation of the findings at scientific conferences.

III. Required documents:

• Letter of application to the Director of IBCH PAS with a statement confirming that the Institute shall be the candidate’s primary place of employment, along with a consent for the Institute to include the recruited employee in the N figure.
• Copy of the doctoral diploma, or an official letter confirming the scheduled date of the PhD defense.

Scientific CV encompassing a track record of previous education and employment, and list of papers published in journals listed in the Web of Science (WoS) database, stating the IF in accordance with WoS, number of citations and the H-index.

4. Contact details of at least one previous scientific supervisor or another researcher who can deliver a letter of recommendation.

Eligibility criteria

VII. The recruitment procedure shall be concluded no later than 04.12.2026

VIII. Employment shall take place in compliance with the provisions of the Labor Code of Poland. The position is available from 1st January 2027. Remuneration: 7750 PLN gross/month.

Selection process

For additional information please contact the Principal Investigator:

Pursuant to the stipulations of the regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation), further referred to as GDPR, we hereby inform that:

• The Institute of Bioorganic Chemistry, Polish Academy of Sciences, seated in Noskowskiego St. 12/14, 61-704 Poznan; REGON 000849327, NIP 777-00-02-062 is the administrator of the collected personal data (further referred to as the Institute).
• The Administrator appointed a Data Protection Officer, who can be contacted in writing, via traditional mail, by sending a letter to the following address: Z. Noskowskiego St. 12/14, 61-704 Poznan, or by sending an e-mail to: [e-mail] .
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• Your personal data shall be subjected to processing for period of 3 months upon the date of decision of the recruitment committee. Following this period, the data will be irretrievably and effectively destroyed.
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  • data transferring, pursuant to article 20 of GDPR;
  • withdraw consent at any moment, without influencing compliance with the law of the processing that was executed prior to consent withdrawal;
  • file a complaint to the Inspector General for Personal Data Protection.

Providing personal data in the scope stipulated in article 22 (1) of the Act of 26 June 1974 – The Labor Code is mandatory, whereas providing data in a broader scope is voluntary and requires consent for its processing.

Protection for whistleblowers

In the case of reporting violations using a dedicated system for whistleblowers, the reporting person's data will be processed in accordance with applicable provisions on the protection of personal data, including the above-mentioned Regulation (EU 2016/679 of 27 April 2016). We ensure confidentiality and protection of the identity of reporting persons, and that their data will not be disclosed without their consent, unless the law provides otherwise.

Detailed rules regarding the protection of personal data and procedures for reporting violations of the law can be found in our Regulations on internal reporting at the Institute of Bioorganic Chemistry, Polish Academy of Sciences, available at the link: