Pharma Process Engineer: Scale-Up & API Development

Carryfor Pharmaceutical Pvt. Ltd.; Karachi Division; On-site; PKR 2,400,000 - 3,200,000; Full time

Benefits offered by this job

Communication

Gratuity

Incentive Bonus

Leaves

Medical

Provident Fund

Transport

Job summary

Carryfor Pharmaceutical PVT LTD in Karachi, Pakistan, is seeking a Chemical Process Engineer to lead process development, scale-up and production for pharmaceutical intermediates and APIs. You will report to the Process Development Lead and collaborate with production, QA and R&D to ensure GMP-compliant manufacturing.

The role emphasizes developing synthesis routes, preparing PFDs, mass and energy balances, and safe operations with a strong focus on process safety and continuous improvement.

Qualifications

• Degree in Chemical Engineering or related discipline with strong fundamentals in reaction engineering and unit operations.
• Experience with process development, scale-up and pilot plant operations in pharmaceutical or fine chemical manufacturing.
• Knowledge of GMP, process safety (HAZOP, HIRA) and chemical hazard control measures.
• Practical skills preparing mass/energy balances, PFDs, material specifications and SOPs.
• Familiarity with analytical techniques for impurity control and collaboration with QC labs.
• Experience using process simulation or calculation tools (ASPEN, MATLAB, Excel).
• Strong documentation and change-control practices for regulated manufacturing.
• Master’s degree or professional training in pharmaceutical process development.

Responsibilities

• Develop, optimize and scale chemical synthesis routes and unit operations for API and intermediate production.
• Prepare and review process flow diagrams (PFDs), mass and energy balances, and SOPs.
• Perform process hazard analyses and risk assessments (HAZOP, HIRA) and implement safety controls.
• Support troubleshooting of process deviations, yield losses and impurity issues with QA and analytical teams.
• Work on equipment selection, pilot trials, and technology transfer from R&D to manufacturing.
• Monitor process performance and lead continuous improvement activities.

Skills

Reaction engineering

Unit operations

GMP knowledge

HAZOP/HIRA

PFDs

Mass balances

Energy balances

SOPs

Impurity control

Documentation

Change control

Analytical techniques

Education

Chemical Engineering degree

Master’s degree in pharmaceutical process development

Tools

ASPEN

MATLAB

Excel

Job description

Carryfor Pharmaceutical PVT LTD in Karachi, Pakistan, is seeking a Chemical Process Engineer to lead process development, scale-up and production for pharmaceutical intermediates and APIs. You will report to the Process Development Lead and collaborate with production, QA and R&D to ensure GMP-compliant manufacturing.

The role emphasizes developing synthesis routes, preparing PFDs, mass and energy balances, and safe operations with a strong focus on process safety and continuous improvement.