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Simula Research Laboratory in Oslo seeks a two-year Postdoctoral fellow to work on the aCleanBrain project, advancing mathematics, algorithms, and software for brain clearance modeling during sleep. You will join an interdisciplinary team and contribute to novel numerical methods and machine learning approaches.
The project is funded by ERC advanced grant, with expected start January 2027, offering a competitive salary and strong opportunities for international collaboration.
Simula Research Laboratory AS is a publicly owned research laboratory located in Oslo, Norway. Simula's mission is to solve important and fundamental problems of science and engineering, with the main goal of benefiting and advancing society. Simula conducts Information and Communication Technology (ICT) research in the fields of scientific computing, software engineering, communication systems, machine learning and cybersecurity.
In the Department for Scientific Computing and Numerical Analysis at Simula, we now have an opening for 1 Postdoctoral fellow to join our research project: aCleanBrain - BRAIN FLUIDS - TRANSPORT AND CLEARANCE.
The successful candidate will join the aCleanBrain core research team consisting of several other PhD candidates, Postdoctoral fellows, senior researchers as well as national and international collaborators, and become an integral part of the large, vibrant and open research environment within scientific computing, applied mathematics and computational physiology at Simula.
The aCleanBrain research project is all about developing new mathematics, algorithms, and software tools in order to better understand the process of brain clearance, in particular during sleep. This project is a highly interdisciplinary project involving collaborations with medical experts, scientific software development, the use of both traditional simulation methods such as finite element methods as well as machine learning in order to answer deep questions of basic brain functions. The research questions require deep mathematics in terms of novel numerical analysis, advanced scientific software development, and new models of the physics of brain fluids. While a Postdoctoral fellow does not need deep competence in all aspects, such a modeling challenge can only by a team with members of different expertise.
Scientific breakthroughs in neuroscience attempt to explain the need for sleep and the develop- ment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases in terms of fluid dynamics: the waste created during the day is cleared away as we sleep or it accumulates. However, a decade of research after the original theory was posed has revealed that the underlying physical mechanisms are still not understood and that advanced mathematical tools are needed.
In this project we propose a research program addressing:
We will exploit reduced order and machine learning methods in addition to finite element solutions. With successful delivery, aCleanBrain will establish the main drivers of brain fluid dynamics, provide a foundation for accurate, efficient and robust algorithms for multi-physics problems and develop a software framework for advanced biomechanical brain simulations.
We are looking for candidates with a solid track record contributing to one (or more) of these aims.
The aCleanBrain project is funded by the ERC advanced grant funding scheme.
We are looking for candidates for a 2-year Postdoctoral fellowship. Candidates should have a solid background in applied mathematics, scientific computing, computational science, bioengineering or related fields, and an interest in contributing to neuroscience. Candidates must have successfully completed their PhD degree by no more than 6 months after the starting date.
Successful candidates should have the following qualifications:
Simula is an equal opportunity employer, and women are particularly encouraged to apply.
October 4, 2026. Applications will be evaluated on a rolling basis, and the preferred start date is January 2027.
Simula Research Laboratory AS is a publicly owned research lab located in Oslo, Norway. Simula conducts Information and Communication Technology (ICT) research in the fields of scientific computing, software engineering, communication systems, machine learning and cybersecurity.
Simula's main objective is to create knowledge about fundamental scientific challenges that are of genuine value for society. This is achieved through high quality research, education of graduate students, industry collaboration, technology transfer, and commercialization. Since 2001, scientific evaluations conducted by the Research Council of Norway has repeatedly placed Simula at the forefront of international research in ICT. In 2025, a new evaluation ranked Simula the highest of all Norwegian research institutions regarding impact and publication quality (p14. in National EVALMIT rapport).
Simula appreciates diversity. We currently employ approximately 200 individuals from 35 countries and strive to create a family-friendly working environment. We are an equal opportunity employer and encourage women to apply.
Simula Research Laboratory uses background checks in our recruitment process.
According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.
Employment for this position will be made according to the act relating to Control of the export of strategic goods, Services and Technology. Candidates who by assessment of the application and any attachments are considered to be in conflict with the export control regulations will not qualify for this position.