Senior Manager Operations COE

7266-Janssen Biologics B.V. Legal Entity; Amsterdam; On-site; EUR 83,000 - 144,000; Full time

Benefits offered by this job

Annual bonus

Vacation days

Parental leave

Well-being reimbursement

Job summary

Johnson & Johnson is seeking a Senior Manager to lead its Center of Expertise in Upstream Processing at the Leiden site. You will guide a team of engineers and supervisors to drive strategic improvements, optimize production, and ensure safety, quality, and compliance across operations.

The role involves cross-functional collaboration with MSAT, QA, MAM, and R&D, monitoring KPIs, and advancing LEAN initiatives while supporting new product introductions and maintaining validated processes per

Qualifications

• Master’s degree in a relevant field.
• 8–10 years in operations management.
• 5+ years in a leadership role.
• Proven ability to lead change.

Responsibilities

• Lead and inspire a high-performing team of engineers and supervisors focused on upstream process, equipment, and quality initiatives.
• Collaborate cross-functionally with Downstream Processing COE, Make Asset Management (MAM), Quality Assurance, MSAT, and R&D to deliver projects on time and within budget.
• Monitor KPIs to ensure safety, quality, reliability, and financial performance.
• Drive operational efficiency in upstream processing through data-driven improvements in yield and performance.
• Lead the introduction of new biopharmaceutical products, ensuring readiness of processes and equipment.
• Maintain validated states of processes and equipment in compliance with GMP.
• Champion LEAN culture through Root Cause Problem Solving, Gemba walks, and process observation.
• Promote diversity, equity, and inclusion within the team.

Skills

Leadership

Analytical skills

cGMP knowledge

Safety awareness

Stakeholder management

Communication

Change leadership

Education

Master’s degree

Tools

BI tools

LEAN methodologies

Six Sigma

Job description

Job Function: Supply Chain Manufacturing

Job Sub Function: Manufacturing Pharmaceutical Process Operations

Job Category: People Leader

All Job Posting Locations: Leiden, South Holland, Netherlands

Job Description

Senior Manager, Center of Expertise - Upstream Processing

Are you a visionary leader with a passion for innovation and operational excellence? Do you thrive in dynamic environments and enjoy empowering teams to deliver impactful results? If so, we invite you to explore an exciting opportunity to shape the future of biopharmaceutical manufacturing!

About the Role

We are seeking a Senior Manager to lead our Center of Expertise (COE) in Upstream Processing at our cutting-edge biopharmaceutical facility in Leiden, the Netherlands. Reporting to the Director of Upstream Processing, you will guide a team of experts dedicated to driving strategic improvements, optimizing production processes, and ensuring the highest standards of safety, quality, and compliance. Your leadership will be instrumental in advancing our manufacturing capabilities, introducing new products, and fostering a culture of continuous improvement and innovation.

Key Responsibilities

• Lead and inspire a high-performing team of engineers and supervisors focused on upstream process, equipment, and quality initiatives. Set clear objectives aligned with business goals, and provide coaching and support to ensure team success.
• Collaborate cross-functionally with departments such as Downstream Processing COE, Make Asset Management (MAM), Quality Assurance, Manufacturing Science & Technology (MSAT), and R&D to deliver impactful projects on time and within budget.
• Monitor key performance indicators to ensure excellence in safety, quality, reliability, and financial performance.
• Drive operational efficiency in upstream processing through data-driven improvements in yield and performance, leveraging deep process and technical expertise.
• Lead the introduction of new biopharmaceutical products, ensuring upstream process and equipment readiness.
• Maintain validated states of processes and equipment in compliance with Good Manufacturing Practices (GMP).
• Champion a LEAN culture through Root Cause Problem Solving, Gemba walks, and process observation.
• Promote diversity, equity, and inclusion, fostering a team culture that reflects and respects the communities we serve.

Qualifications

Must-Have Master’s degree in a relevant field. 8–10 years of industrial experience in operations management, including 5+ years in a leadership role. Proven ability to lead change and solve complex problems. Positive, motivating leadership style that enhances team morale and productivity.

Required Skills

Strong analytical and problem-solving capabilities. High safety and quality awareness, with experience in EHS and cGMP standards. Excellent communication and stakeholder management skills. Deep understanding of operational best practices and industry trends. Demonstrated success in leading change within complex operational environments.

Preferred Skills

Experience in pharmaceutical or upstream processing environments. Project management expertise. Familiarity with LEAN methodologies. Established relationships with external stakeholders.

Preferred Skills

Agile Manufacturing, Business Intelligence (BI), Change Management, Chemistry, Manufacturing, and Control (CMC), Collaboration, Cost-Benefit Analysis (CBA), Developing Others, Gap Analysis, Good Manufacturing Practices (GMP), Inclusive Leadership, Leadership, Manufacturing Compliance, Operational Excellence, Organizational Knowledge, Plant Operations, Process Optimization, Team Management

Additional Information

This role offers a unique opportunity to make a meaningful impact at our Leiden site, while enjoying a collaborative and innovative work culture. Preferred certifications such as Six Sigma Green Belt will further enhance your ability to lead projects and implement process improvements.

Benefits

• Annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions.
• Vacation days
• Parental leave for a minimum of 12 weeks
• Bereavement leave
• Caregiver leave
• Volunteer leave
• Well-being reimbursement
• Programs for financial, physical and mental health
• Service anniversary and recognition awards
• Employees - and in some location’s eligible dependents - can participate in several insurance plans
• For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.

Salary

The anticipated base pay range for this position is: €82,900.00 - €144,210.00

Company Overview

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com. As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at https://www.jnj.com/.

Johnson & Johnson is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.