Scientist

Clear2Cure; Utrecht; On-site; EUR 70,000 - 90,000; Full time

Job summary

Clear2Cure is a preclinical biotech located at Utrecht Science Park seeking a Scientist to join the drug discovery team. You will perform experiments, drive platform development, and help design a completely novel class of therapeutics.

Your role includes designing and optimizing multi-specific drug candidates, developing and troubleshooting assays, and coordinating work with CROs and external partners. The position supports patent filings and grant applications, with a min.

Qualifications

• PhD in a relevant life-science field or equivalent bench track record.
• Strong hands-on experience with cell culture, FACS, microscopy, and quantitative cell-based assays.
• Self-sufficient and organized at the bench; you plan, execute, and document your experiments with care.
• Strong ability to clearly communicate complex scientific concepts within an interdisciplinary team.
• Industry experience and/or experience with VHH antibodies or targeted protein degradation is a plus.

Responsibilities

• Designing, engineering, and optimizing novel multi-specific drug candidates.
• Developing, running, and troubleshooting assays to characterize drug candidates.
• Executing studies to understand how drug candidates behave in relevant biological systems.
• Coordinating experimental work with CROs and external partners.
• Working with the leadership team on patent filings and grant applications.

Skills

Independent work

Communication

Adaptability

Education

PhD in a life-science field

Tools

Cell culture

FACS

Microscopy

Quantitative cell-based assays

Job description

Clearbody ® Discovery & Development | Utrecht Science Park | Full-time (1 year)

About Clear2Cure

Clear2Cure is a preclinical-stage biotech company developing a new class of extracellular targeted protein degraders (eTPD). Our Clearbodies® are bi- and multi-specific VHH-antibodies that bind disease targets and trigger their lysosomal degradation. This creates a new way to drug targets that conventional small molecules and biologics struggle to reach efficiently. We are well-funded and moving quickly in a new frontier of drug development.

The role

We are hiring a Scientist as a key member of our drug discovery team. In this role, you will perform experiments, drive platform development and help design a completely novel class of therapeutics.

Your responsibilities will include:

• Designing, engineering, and optimizing novel multi-specific drug candidates.
• Developing, running, and troubleshooting assays to characterize drug candidates.
• Executing studies to understand how drug candidates behave in relevant biological systems.
• Coordinating experimental work (in vitro and in vivo) with CROs and external partners.
• Working with the leadership team on patent filings, and grant applications.

Who you are

• High agency: You take ownership, move quickly from idea to experiment, and hold yourself to a high bar.
• Ambitious: You bring energy to the lab and enjoy building something ambitious with a small team.
• Adaptable: You can shift smoothly between different types of work and remain effective and optimistic when priorities, plans, roadmaps, and responsibilities change.
• Resilient: Early-stage startups can be demanding, and discovering new drugs is difficult. You’ve demonstrated the persistence to tackle difficult problems and stay committed over the long term.

Qualifications

• PhD in a relevant life-science field (e.g. immunology, molecular biology, cell biology, pharmacology) or an equivalent, demonstrable track record at the bench.
• Strong hands-on experience with cell culture, FACS, microscopy, and quantitative cell-based assays.
• Self-sufficient and organized at the bench; you plan, execute, and document your experiments with care.
• Strong ability to clearly communicate complex scientific concepts within an interdisciplinary team.
• Industry experience (biotech/pharma) and/or experience with VHH antibodies, antibody engineering, or targeted protein degradation is a strong plus; the ability to learn fast and work hard matters even more.
• You are authorized to work in the Netherlands.

What we offer

• A min. 1-year full-time appointment with real ownership and the opportunity to grow your role as the company scales.
• Direct collaboration with the founders and access to an experienced network of advisors.
• A competitive compensation package.

Applications are reviewed on a rolling basis, and we will proceed as soon as we find the right candidate.