RNA Therapeutics Study Physician | Medical Director

ProQR Therapeutics N.V.; Netherlands; On-site; EUR 120,000 - 180,000; Full time

Benefits offered by this job

Annual performance bonus

Stock options

Pension plan

Commuting allowance

Snacks and drinks

Employee events

Job summary

ProQR Therapeutics N.V. in Leiden, Netherlands seeks a Study Physician / Medical Director to guide early clinical development of RNA-editing therapies. The role combines hands-on medical oversight with strategic input and cross-functional collaboration across Clinical Development.

The appointment level depends on experience, and the on-site position reports to the Clinical Development Lead. Fluency in English is required.

Qualifications

• Medical degree from an accredited institution.
• Excellent written and spoken English.
• Hands-on experience with design, conduct, medical monitoring of industry-sponsored studies.
• Experience reviewing clinical and safety data and contributing to safety/regulatory documents.
• Strong understanding of drug development and regulatory requirements.

Responsibilities

• Lead or contribute to design and authoring of study concepts, protocols and amendments for first-in-human and early-phase trials.
• Provide medical oversight and act as medical monitor for assigned studies, safeguarding safety and data integrity.
• Review emerging clinical data (AEs, labs, PK/PD, biomarkers) and support benefit-risk assessments.
• Contribute to development strategy for rare/orphan diseases, including endpoints and biomarkers.
• Represent the study to investigators, sites and external stakeholders; collaborate with cross-functional teams.

Skills

Medical judgment

Data interpretation

Cross-functional collaboration

English proficiency

Communication in English

Education

Medical degree

Tools

ICH-GCP

Clinical data systems

Job description

ProQR Therapeutics N.V. in Leiden, Netherlands seeks a Study Physician / Medical Director to guide early clinical development of RNA-editing therapies. The role combines hands-on medical oversight with strategic input and cross-functional collaboration across Clinical Development.

The appointment level depends on experience, and the on-site position reports to the Clinical Development Lead. Fluency in English is required.