PhD in Single-Molecule Biophysics & Computation for Therapeutics

Delft; Delft; On-site; EUR 37,000 - 47,000; Full time

Job summary

TU Delft seeks a motivated PhD student to investigate molecular interactions using single-molecule techniques and computational tools. The project focuses on protein-ligand and protein-peptide interactions, combining experimental and computational methods to generate multiplexed data and validate ML predictions.

The position is part of a Marie Skłodowska-Curie Doctoral Network, with mobility requirements and a four-year employment structure under the Dutch university system.

Qualifications

• MSc degree (or nearing completion) in physics, biophysics, computational biology, or a related field.
• Strong programming skills (Python) and experience in data analysis and computational methods.
• Familiarity with molecular biology techniques.
• Excellent written and spoken English skills.
• Ability to work effectively in a collaborative, international, and interdisciplinary environment.

Responsibilities

• Apply single-molecule techniques to study molecular interactions and mechanisms.
• Obtain single-molecule multiplexing data and validate machine learning predictions with high-throughput data.
• Collaborate with international partners for therapeutic applications of the research.

Skills

Python programming

Data analysis

English proficiency

Collaborative work

Education

MSc degree in physics/biophysics/computational biology

Job description

TU Delft seeks a motivated PhD student to investigate molecular interactions using single-molecule techniques and computational tools. The project focuses on protein-ligand and protein-peptide interactions, combining experimental and computational methods to generate multiplexed data and validate ML predictions.

The position is part of a Marie Skłodowska-Curie Doctoral Network, with mobility requirements and a four-year employment structure under the Dutch university system.