Manufacturing Operator

Biopharma Careers; Sassenheim; Presencial; EUR 35.000 - 53.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Health insurance

Pension plan

Commuting allowance

Bonus program

Descripción de la vacante

Johnson & Johnson is seeking Manufacturing Operators for USP/DSP and Fill & Finish in Sassenheim, Netherlands, to support cell expansion, virus production, purification, and automated filling under GMP and BSL2 conditions. You will join our fully digital Lenti Viral Vector Facility preparing for commercial production mid-2026.

You will install and operate equipment, write training sheets, perform GMP documentation, raise deviations, and contribute to continuous improvement while working shifts

Formación

• MBO4/HBO in lab, biotechnology, biomedicine, process tech, or equivalent with biotech/biopharma experience.
• Hands-on expertise in a BSL2 environment focusing on cell culture, virus propagation, purification, or Fill & Finish.
• Strong English communication and independent work capability.

Responsabilidades

• Support installation and operation of new equipment and write job breakdown sheets.
• Collaborate in daily tasks and department support activities according to procedures and schedules.
• Perform GMP documentation, raise deviations and identify process gaps; train operators where needed.
• Contribute to continuous improvement of processes and procedures while working safely.

Conocimientos

Administrative Support

Agile Manufacturing

Analytics Dashboards

Communication

Data Savvy

Process Optimization

Team Collaboration

Educación

MBO/HBO in biotech or related field

Herramientas

Automated filling robot

BSL-2 lab environment

Descripción del empleo

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com .

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Supply Chain Manufacturing

Job Sub Function:

Manufacturing Pharmaceutical Process Operations

Job Category:

Business Enablement/Support

All Job Posting Locations:

Sassenheim, Netherlands

Job Description:

We are looking for the best Manufacturing Operators for our USP/DSP and Fill and Finish departments in Sassenheim, Netherlands!

Join our fully digital Lenti Viral Vector Facility in Sassenheim, producing vectors for multiple myeloma treatment impacting 160,000 patients worldwide. As we prepare for commercial production in mid-2026, we’re looking for Manufacturing Operators (USP/DSP/F&F) to support cell expansion, virus production, purification, and automated filling under GMP and BSL2 conditions.

Build your career at the forefront of innovation in a collaborative environment, with strong growth opportunities through training, mentoring, and clear career paths.

As a Manufacturing Operator, you will Support the installation and operation of new equipment, writing job breakdown sheets for training and work instructions. Collaborating in the execution of the daily task and the supporting activities of the department according to procedures and detailed schedule. Perform process and GMP documentation activities raise process deviations, notice process gaps, and tackle them, train operators. Contribute to continuous improvement of processes and procedures Work safely and compliantly in line with GMP, EHS, and quality standards.

Qualifications / Requirements:

• Preferably an MBO 4 or HBO in laboratory & biotechnology, biochemistry, biomedicine, process technology, allround laborant OR equivalent education level with proven experience in biotech or biopharma manufacturing.
• Hands‑on expertise in a BSL2 environment, focusing on cell culture, virus propagation, purification, or Fill & Finish, adhering to GMP and EHS standards.
• Strong English communication skills, with the ability to analyse complex situations and maintain high accuracy and independence.
• Adaptable teammate with a proactive approach, ready to tackle challenges and work flexible shifts.

Your Benefits:

• 12-month contract incl. 1 month probation period
• 40-hour work week, shifts to be implemented.
• 36 days of paid leave, based on a full-time contract.
• J&J Health Insurance with Zilveren Kruis Achmea.
• J&J Pension Plan
• Commuting allowance
• Global Well-Being Reimbursement up to 450EUR*
• Referral bonus, refer your friends and family to work at J&J.
• Working Jubilee Gifts
• Global Parental leave
• Career Opportunities to keep growing on your skills
• In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, and programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans.

About the departments:

Upstream Processing (USP)

The USP department focuses on culturing cells and infecting them with a virus. The team operates on a 13/7 shift roster with 19,99% shift allowance.

Key activities include:

• Culturing and inoculation of cells in Shaker Flasks and Wave bags
• Daily monitoring of cell cultures (cell count, pH, sampling)
• Preparing and executing transfection processes
• Preparing process additions (e.g. Benzonase solutions)
• Harvesting and clarification of cell culture material
• Sample handling and documentation for USP activities

Downstream Processing (DSP)

The DSP department is responsible for the purification of viral vectors. The team operates on a 13/7 shift roster with 19,99% shift allowance.

Key activities include:

• Purification using Ion Exchange chromatography
• Sterile filtration, including filter integrity testing (PUPSIT)
• Ultrafiltration and diafiltration
• Sample handling and documentation for DSP activities

Fill & Finish (F&F)

The F&F department performs the final filling, preparation, freezing, and storage of the product. The team operates on a 16/7 with a shift allowance with 26,19% shift allowance.

Key activities include:

• Preparation and setup of isolators and filling equipment
• Aseptic filling in a Grade A isolator using an automated filling robot
• Visual inspection of filled vials
• Labelling and storage of product in controlled freezers

At Johnson & Johnson, we want every candidate to feel supported throughout the hiring process. Our goal is to make the experience clear, fair, and respectful of your time.

Required Skills:

• Administrative Support
• Agile Manufacturing
• Analytics Dashboards
• Chemistry
• Manufacturing, and Control (CMC)
• Communication
• Data Compilation
• Data Savvy
• Execution Focus
• Gap Analysis
• Good Manufacturing Practices (GMP)
• Operational Excellence
• Plant Operations
• Process Optimization
• Process Oriented
• Project Administration
• Regulatory Compliance
• Self-Awareness

Preferred Skills:

• Administrative Support
• Agile Manufacturing
• Analytics Dashboards
• Chemistry
• Manufacturing, and Control (CMC)
• Communication
• Data Compilation
• Data Savvy
• Execution Focus
• Gap Analysis
• Good Manufacturing Practices (GMP)
• Operational Excellence
• Plant Operations
• Process Optimization
• Process Oriented
• Project Administration
• Regulatory Compliance
• Self-Awareness

The anticipated base pay range for this position is:

€35.000,00 - €53.360,00

Benefits:

• In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, and programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.