Senior Site Reliability Engineer III for Amgen's biopharmaceutical digital platforms in Hyderabad — ensure reliability of regulated, life-sciences systems using Kubernetes, Terraform and multi-cloud (AWS / Azure / GCP), with SLO-driven reliability engineering and GxP-grade compliance. 6+ years, hybrid Hyderabad, INR 26-46 LPA band.
About this role and the team at Amgen. Senior Site Reliability Engineer III for Amgen's biopharmaceutical digital platforms in Hyderabad — ensure reliability of regulated, life-sciences systems using Kubernetes, Terraform and multi-cloud (AWS / Azure / GCP), with SLO-driven reliability engineering and GxP-grade compliance. 6+ years, hybrid Hyderabad, INR 26-46 LPA band. The role is permanent / full-time, hybrid, and the salary band reflects market rates in Hyderabad as of mid-2026 (confirmed at the offer stage).
Responsibilities
- Build and operate highly-available systems with Kubernetes and Docker for Amgen's biopharmaceutical digital platforms — services that support research, manufacturing and commercial functions where reliability and data integrity carry regulatory weight.
- Implement infrastructure-as-code with Terraform across multiple cloud providers (AWS, Azure and GCP), authoring reusable, validated modules so that teams can stand up compliant environments from a single template.
- Establish observability and proactive reliability engineering — Prometheus / Grafana and cloud-native monitoring, meaningful SLIs and SLOs, alerting tuned so that patient- or quality-impacting incidents elevate within minutes while noise is suppressed.
- Own incident management end to end: on-call rotation, rapid triage, blameless post-incident reviews, and automation of remediation so recurring issues are engineered away rather than re‑fought.
- Ensure security, compliance and performance in a regulated environment — GxP, FDA 21 CFR Part 11, GAMP-5 and comparable frameworks — producing the change records, validation artefacts and audit trails that survive inspection, and treating documentation as code wherever possible.
- Drive disaster-recovery and business‑continuity engineering: multi-region failover, tested point‑in‑time restore, and resilience patterns proven through regular game‑days rather than assumed.
- Collaborate on cloud migrations and modern‑architecture adoption — moving legacy workloads to cloud‑native, containerised designs without compromising the validated state that regulated systems require.
- Reduce toil through automation and self‑service tooling, and partner with development and quality teams to shift reliability and compliance left into design and CI.
- Mentor SREs and graduate engineers, run knowledge‑sharing sessions on Kubernetes, Terraform and reliability practice, and represent the Hyderabad SRE team in global architecture and reliability forums.
Requirements
- 6+ years in Site Reliability Engineering / DevOps with strong, hands‑on production Kubernetes and container (Docker) experience.
- Terraform across at least one — ideally two or three — of AWS, Azure and GCP: reusable modules, remote state per environment, plan reviews for cost and security.
- Observability and SRE fundamentals: Prometheus / Grafana (or cloud-native equivalents), SLIs / SLOs, error budgets, on‑call discipline, and blameless post‑mortems.
- Strong scripting / programming, Python preferred, for reliability tooling and automation.
- Working understanding of regulated software environments — GxP, FDA 21 CFR Part 11, GAMP-5, SOX or HIPAA — and the validation and change‑control implications they bring.
- Disaster‑recovery and high‑availability design experience (multi‑region, failover, tested restores).
- Excellent written communication — you will author change records and validation artefacts read by auditors and regulators.
- Life‑sciences / pharma or other regulated‑industry experience is a strong plus.
- Bachelor's or higher in CS / Engineering or a numerate science; cloud and Kubernetes certifications valued.
Why this role in 2026
Amgen is a leading global biotechnology company, and its Hyderabad capability centre is one of its principal engineering hubs. A Senior SRE III seat here is a rare blend — multi-cloud Kubernetes and Terraform reliability engineering combined with GxP‑grade regulated‑software discipline — a combination that is scarce in the market and tends to leverage into senior platform or SRE‑leadership roles in life sciences or pharma‑tech within a few years. The work is meaningful (it supports getting medicines to patients reliably), the compensation is strong, and the regulated rigour builds genuinely differentiated experience.
Company & benefits
INR 26-46 LPA fixed band plus target bonus (market-rate estimate; confirmed at offer). Amgen restricted‑stock eligibility for senior individual contributors. Comprehensive private medical for self + family + parents. Hybrid working in Hyderabad. Sponsored cloud / Kubernetes certifications. Generous leave and parental‑leave policies, on‑site wellness and mental‑health support, and the mission of serving patients.