Scientist

Enzene Biosciences Ltd; Pune District; On-site; INR 800,000 - 1,500,000; Full time

Job summary

A leading biopharmaceutical company seeks a skilled scientist with expertise in downstream process activities to join their team. The candidate will be responsible for planning and executing process development for protein purification, ensuring consistency and reliability while collaborating with internal teams. A Master's degree in biological sciences and 8-11 years of experience are required. Proficiency in analytical techniques and strong communication skills are essential. This role involves cross-functional collaboration and technical troubleshooting within the lab.

Qualifications

• 8–11 years of experience in related field.
• Proficiency in analytical techniques for proteins.
• Ability to work independently and lead small teams.

Responsibilities

• Plan and execute downstream process activities.
• Responsible for documentation and reporting activities.
• Troubleshoot technical problems in manufacturing.

Skills

Protein purification process development expertise

Troubleshooting ability

Data analytics skills

Communication

Teamwork

Education

MSc, M.Tech, M.Pharm or equivalent Master degree in biological sciences

Tools

Chromatography

HPLC

Gel electrophoresis

Job description

Role & responsibilities

• Planning and execution of Downstream Process activities for mammalian and/or microbial products / recombinant protein along with team members under supervision of manager for multiple projects
• Accountable for ground level planning, execution, data capturing, compilation, and interpretation in coordination with the reporting manager
• Accountable for reviewing of draft presentation and discussion with the help of team members
• Attending and representing department in internal and external meetings
• Accountable for review / drafting of documentation activities like preparation of development reports, BPR, SOP, EOP, IOP
• Accountable for planning and decision‑making discussion regarding activity priorities and providing information on the feasibility of prospective projects to reporting manager
• Responsible for troubleshooting of technical problems at manufacturing by discussion and execution
• Scientist shall be accountable for lab management activities (maintaining lab cleanliness, equipment maintenance, etc.)
• Scientist is accountable for cross‑functional communication with internal and external vendors/clients for technical queries in consultation with reporting manager
• The candidate shall be accountable for maintaining environment, health, and safety (EHS) requirements at workplace to ensure individual and lab/plant safety.

Technical Skill Requirement

• Protein purification process development expertise and hands‑on experience with troubleshooting ability (chromatography, depth filtration, centrifugation, UFDF, sterile filtration, etc.) in mammalian/microbial expressed antibodies and/or therapeutic proteins
• Accountable for the execution and monitoring of processes to ensure consistency and reliability. Experience in process development using Quality by Design (QbD), and DoE‑based process development
• Hands‑on experience with data analytics using different statistical tools will be added advantage. Experience of scale‑up/down, technology transfer (TT) activities and virus clearance (VCS) studies for multiple products
• Accountable for upkeeping the lab in running state from equipment and compliance aspect [setup, operation, troubleshooting and routine maintenance of purification equipment (chromatography system, pH/conductivity meter, UFDF system, etc.)]
• Strong commitment and dedication towards work, enthusiasm, motivation, and persuasive ability in a team and experience of leading a team of 1–2 members will be added advantage
• Candidate should be able to work independently, analyse and interpret experimental data, and present/document experimental results at meetings
• Proficiency in protein analytical techniques (e.g., protein assay, gel electrophoresis, HPLC, etc.) is an added advantage

Experience & Qualification

MSc, M.Tech, M.Pharm or equivalent Master degree in biological sciences from a recognised university.

Experience Range: 8–11 years.

SoftSkill Requirement

Communication and teamwork.