Research Associate - Mass Spectrometry LCMS

Dr. Reddy's Laboratories; Bachupalle; On-site; INR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Relocation support

Medical coverage

Life coverage

Maternity & Paternity benefits

Learning & development

Job summary

Dr. Reddy’s Laboratories Ltd. is seeking an experienced LCMS specialist to design and execute protein characterization studies for biosimilars.

The role focuses on developing robust LCMS methods for intact mass, subunit mass, and PTM analysis, contributing to the advancement of Biologics development. The candidate should hold a Master’s or PhD in proteomics/biotechnology/biochemistry with 2–5 years (or 0–1 for PhD) of relevant experience in method development and handling HRMS, TQ LCMS, Synapt,

Qualifications

• Master degree with 2-5 years or PhD with 0-1 years in method development and qualification.
• Experience handling analytical instruments like HRMS, TQ LCMS, Synapt, Xevo QTOF, and 2D LC QTOF.

Responsibilities

• Design and execute LCMS experiments for protein characterization and biosimilar analysis.
• Develop and qualify methods for biosimilar analytical characterization (intact mass, subunits, PTMs).
• Interpret data, generate reports, and present results to cross-functional teams.
• Ensure GDP compliance and maintain safe laboratory practices.

Skills

LCMS

Proteomics

QTOF

Biosimilars

Method development

Analytical instruments

Education

Master’s degree in Proteomics/Biotechnology/Biochemistry

Ph.D. in Proteomics/Biotechnology/Biochemistry

Tools

HRMS

TQ LCMS

Synapt

Xevo QTOF

2D LC QTOF

Job description

Job Description:

Company Description

Dr. Reddy’s Laboratories Ltd. is a leading multinational pharmaceutical company based across global locations. Each of our 24,000 plus employees comes to work every day for one collective purpose: to accelerate access to affordable and innovative medicines because Good Health Can’t Wait.

We started in 1984 with a modest investment, 20 employees and a bold vision. Today, we have research and development centres, manufacturing facilities or a commercial presence in 66 countries.

For nearly four decades, we have stood for access, affordability and innovation based on the bedrock of deep science, progressive people practices and robust corporate governance. As the pharmaceutical industry evolves and undergoes disruption, we see an opportunity – to strengthen our core further (the next steps) and to build the future (the new bets).

‘The Next and the New’ is how we aim to continue to be the partner of choice – purpose-driven, future-ready and sustainable. Our aim is to reach over 1.5 Bn+ patients across the world by 2030 by growing our core businesses and building for the future with sustainability at the core of our purpose and strategy. Sustainability for us means operating in a manner that respects people, planet and purpose – helping us conserve precious resources, serve our patients, create value for stakeholders, give back to society, fulfil our potential and maintain our integrity and transparency

Dr Reddy’s maintains a work environment, free from discrimination and is an equal opportunity employer. We are committed to employ & nurture all qualified diverse workforce without regard to race, colour religion, nationality, sex, age, disability status, genetics, sexual orientation, gender expression, citizenship or any other characteristic or classification protected by applicable law(s) of the country we operate in. We treasure every talent, and recognize merit and diversity in our organization.

Job Description

Job Summary

We are looking for an experienced professional to design and execute LCMS experiments for protein characterization. The primary objective is to develop a robust methods using LCMS for CAA/Bio-similarity, contributing to the advancement and success of the team's objectives within the product development domain.

Roles & Responsibilities

• Deep understanding on protein/mAbs characterization using LC-MS/MS (QTOF, MALDI TOF, 2D LC QTOF, IM QTOF etc.).
• Complete, in-dept knowledge on Biosimilars characterization (Intact mass analysis, subunit mass, peptide mapping, PTM analysis, etc.) using LC-MS/MS.
• Experience on mAbs bio similarity, CAA using LCMS.
• Experience on method development and qualification for various mAb’s using LC-MS/MS.
• Knowledge on ADC’s characterization
• Knowledge on HCP and MAM workflows is preferred.
• Preferred knowledge on Targeted proteomics/Protein quantitation, Impurities analysis and spent media analysis using TQLCMS
• Characterization of SSR/Signal peptides
• Understanding on good laboratory practices and Good Documentation Practices.
• The candidate should have good knowledge and skills to independently plan and execute method development and validation activities for the functional characterization.
• To take up new technology initiatives within the development group and to draft primary documents.
• Interpret data, draw conclusions, and present data results at group meetings and other forums.
• Prepare protocol / report / manuscript as needed, including contributions to writing and reviewing content.
• Collaborate with cross-functional teams to support development projects.
• Ensuring compliance with Good Documentation Practices (GDP).
• Ensure safe practices in the facilities and participate in the organization-based safety and quality initiatives.

Qualifications

Educational Qualification

A Master’s degree (M.Sc. or M.Tech. or or M.Pharm.) or Ph.D. in Proteomics, Biotechnology, Biochemistry.

Minimum Work Experience

• Master degreewith minimum 2-5years or PhD with 0-1years of working experience onMethod development, qualification, Handling of analytical instruments like HRMS, TQ LCMS, Synapt, Xevo QTOF, 2D LC QTOF etc.

Skills & Attributes Technical Skills

• An understanding of the analytical DevelopmentforBiotherapeutics/ Biosimilars.
• In-depth knowledge LCMS QTOF.
• Deep understanding of analytical techniques, statistical analysis, data management and analysis.

Behavioral Skills

• Possesses team-building capability, fostering positive collaboration and cohesion.
• Good verbal and written communication skills, facilitating effective interaction.
• A strong learning ability, quickly acquiring new knowledge and skills.
• Is self-motivated, taking initiative and showing enthusiasm for tasks and responsibilities.
• Exhibits troubleshooting skills, effectively identifying and resolving issues.
• Good interpersonal skills, fostering positive relationships and effective communication.

Additional Information

About the Department
Biologics

Currently operates in the Global Biosimilars business - a segment that is poised for attractive and sustained growth over the next 10–15-year time horizon.
With a robust portfolio of biosimilar products across key therapeutic areas, covering ~US$80+ Bn in innovator sales – future business pipeline covers a variety of product classes and therapy areas, and new modalities. Fully integrated organization with over two decades of experience in developing, manufacturing and commercializing multiple biosimilar products.
With a Product Development engine that has end-to-end capabilities – in-house clone development, upstream and downstream process development, bioanalytical development and proprietary formulation.
Supported by a Clinical and Regulatory team with experience in executing complex biosimilar programs with innovative global trial designs.
We have a proven experience in commercial-scale manufacturing across a variety of technology platforms with global quality standards and a highly competitive cost structure
Rich experience of commercializing high-quality biosimilars in multiple markets with over 900,000 patients having benefited from our products till date.

Benefits Offered

• At Dr. Reddy’s we actively help to catalyse your career growth and professional development through personalised learning programs.
• joining & relocation support
• family support (Maternity & Paternity benefits)
• learning and development opportunities
• medical coverage for yourself and your family
• life coverage for yourself

Our Work Culture

Ask any employee at Dr. Reddy’s why they come to work every day and they’ll say, because Good Health Can’t Wait. This is our credo as well as the guiding principle behind all our actions. We see healthcare solutions not only as scientific formulations, but as a means to help patients lead healthier lives, and we’re always attuned to the new and the next to empower people to stay fit. And to do this, we foster a culture of empathy and dynamism. People are at the core of our journey over the last few decades. They have been supported by an enabling environment that buoys individual ability while fostering teamwork and shared success. We believe that when people with diverse skills are bound together by a common purpose and value system, they can make magic.

For more details, please visit our career website athttps://careers.drreddys.com/#!/

• Job Family: Research & Development
• Sub Job Family: Analytical R&D - Biosimilar
• Business unit: Biologics

Requirements: