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St Johns Research Institute (SJRI) invites applications for Project Research Scientist-I (Non-Medical) to oversee day-to-day implementation of the eSPOT Study in Karnataka. You will coordinate CHO training, field activities, and staff management while ensuring protocol adherence and high-quality data collection.
The role includes supervising recruitment, follow-up, and data quality, organizing meetings, and supporting budget tracking and reporting for ICMR collaborations.
Location: Bangalore
The eSPOT study evaluates the effectiveness and implementation of a brief, scalable psychological intervention for reducing depression among adults with diabetes mellitus and/or hypertension attending Ayushman Arogya Mandirs (AAMs) in Karnataka. The intervention combines Single-Session Problem-Solving Therapy (SSPST) delivered by Community Health Officers (CHOs) with Short Digital Video Support (SDVS) and is designed for integration into routine NCD care. eSPOT Study full Protocol Objectives:
1. To pilot test the preliminary effectiveness and feasibility of SSPST supplemented with SDVS, assessing recruitment, retention, intervention fidelity, acceptability, and preliminary changes in PHQ-9 scores among 40 participants.
2. To evaluate the effectiveness and implementation of the intervention over 12 months by assessing changes in depression scores at 3, 6, and 12 months, along with implementation outcomes including Reach, Effectiveness, Adoption, Implementation, Maintenance, fidelity, and integration into routine NCD services. eSPOT Study full Protocol
3. To estimate the incremental cost and cost-effectiveness of the intervention from the health-system perspective. eSPOT Study full Protocol Methods: It will be a prospective, single-arm pilot study followed by a Hybrid Type 1 effectiveness-implementation study using a mixed-methods approach. Adults with diabetes mellitus and/or hypertension who screen positive for depression will be recruited from selected AAMs in Karnataka. Trained CHOs will deliver a 20-30-minute SSPST session, supplemented by a 10-15-minute digital video module for home-based reinforcement. Participants will be assessed at baseline and followed up at 3, 6, and 12 months. Effectiveness will be evaluated primarily using PHQ-9 scores, along with anxiety, quality of life, problem-solving ability, clinical indicators, and treatment adherence. Implementation will be assessed using the RE-AIM framework, supported by qualitative interviews and focus group discussions. A trial-based economic evaluation will assess the costs and cost-effectiveness of the intervention.