Principal Software Engineer

Amgen Inc. (IR); Hyderabad; On-site; INR 3,500,000 - 7,000,000; Full time

Benefits offered by this job

Total Rewards Plans

Job summary

Amgen invites a Principal Software Engineer to lead architecture for AI platforms powering chatbots, agents, and AI-enabled workflows across manufacturing and engineering use cases. You will define reference architectures, evaluate build-versus-buy options, and own reliability and cost characteristics.

This hands-on, leadership role requires deep manufacturing technology fluency, cloud-native experience with Kubernetes and data platforms, and strong collaboration with product owners and senior

Qualifications

• Master’s / Bachelor’s degree in Computer Science, Engineering, or equivalent.
• 13-17 years of engineering experience building or platforming cloud services or developer platforms.
• 3+ years leading engineering teams or technical programs.
• Hands-on experience with cloud-native platforms using Kubernetes, containers, and microservices.
• Experience with LLM serving, inference endpoints, routing, scaling, and latency/cost optimization.
• Familiarity with API gateway patterns, authentication, and secure integrations.
• Strong collaboration with product managers and stakeholders.

Responsibilities

• Define technical vision and reference architecture for AI platforms.
• Translate requirements into scalable platform capabilities, including hosting, model access, gateways, observability, and tooling.
• Lead decisions on LLM serving, model endpoints, caching, and multi-model support.
• Architect manufacturing integrations for data connectivity (SCADA, MES, ERP, LIMS).
• Own platform reliability, cost, capacity planning, and FinOps practices.
• Mentor engineers delivering platform services and CI/CD pipelines.
• Establish security and governance standards for data handling and access controls.
• Prototype architectures, review designs, and participate in code reviews.

Skills

Manufacturing AI

Platform architecture

Kubernetes

LLM serving

DevOps

Observability

Security & governance

Leadership

Communication

Education

Master’s or Bachelor’s in CS/Engineering

Tools

Kubernetes

CI/CD

LangChain

LangGraph

LlamaIndex

OpenAI APIs

Databricks/Spark

Job description

Career Category Manufacturing Job Description

Join Amgen's Mission to Serve Patients If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together-researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Principal Software Engineer Live

What you will do

We are developing Manufacturing and Engineering AI tools that help employees gain insights, access knowledge, and make better decisions more efficiently. The Principal Software Engineer will set the technical direction and lead architecture for platform initiatives supporting chatbots, agents, and AI-enabled workflows across manufacturing and engineering use cases. This role requires deep manufacturing technology fluency and hands-on experience with the platform stack behind industrial and enterprise AI solutions. You will guide architecture and standards for systems that integrate with manufacturing data sources, operational platforms, and modern GenAI services, while supporting both low/no-code and pro-code development patterns. This is a hands-on technical leadership role. You will define architecture, evaluate build-versus-buy options, own reliability and cost characteristics, and lead a team of engineers working with product owners and principal engineers to evolve and operate these platforms.

Win

• Define the technical vision and reference architecture for AI platforms supporting chatbots, agents, orchestration, and related enterprise services.
• Translate product and business requirements into scalable platform capabilities, including agent hosting, model access, AI gateways, observability, and operational tooling.
• Drive platform decisions around LLM serving, model endpoints, caching, batching, latency-versus-cost tradeoffs, and multi-model support.
• Lead architecture for manufacturing integrations and industrial data connectivity, including patterns for SCADA, Data Historian, MES, ERP, LIMS, APIs, event streams, and document-based knowledge sources.
• Own platform reliability, scalability, and cost by defining SLIs/SLOs, capacity planning, cost attribution, and FinOps practices.
• Collaborate with Product Owners, Principal Engineers, and stakeholders to define roadmap, acceptance criteria, and delivery milestones.
• Lead and mentor engineers delivering platform services, integrations, CI/CD for agents and models, and marketplace/catalog capabilities.
• Establish standards for security, compliance, and model governance, including data handling, access controls, logging, auditability, and traceability.
• Be hands‑on when needed to prototype architectures, review designs, troubleshoot production incidents, and participate in code and design reviews.

Technology and domain experience

The ideal candidate will bring direct experience with manufacturing or industrial technology environments, along with strong fluency in modern AI and data platforms.

• Manufacturing systems and industrial data sources such as SCADA, Data Historian, MES, ERP, and LIMS.
• Cloud and data platforms including AWS, Databricks, Apache Spark, PySpark, Scala, Python, and SQL.
• Real-time and event-driven integration using Apache Kafka, Debezium, or similar streaming technologies.
• GenAI and MLOps capabilities such as MLflow, model serving, experiment tracking, prompt management, deployment automation, and governance.
• AI application frameworks and orchestration tools such as LangChain, LangGraph, LlamaIndex, DSPy, Amazon Bedrock, and OpenAI APIs.
• Knowledge retrieval patterns including RAG, embeddings, vector databases, knowledge graphs, and metadata-driven search.
• Production engineering practices including Kubernetes, containers, microservices, API gateway patterns, CI/CD, automated testing, and observability.
• Agile/SAFe delivery using JIRA, Confluence, and DevOps tooling.

Basic Qualifications:

• Master's / Bachelor’s degree in Computer Science, Engineering, or equivalent practical experience.
• 13-17 years of engineering experience building or platforming cloud services or developer platforms, with 3+ years leading engineering teams or technical programs.
• Proven experience designing and operating cloud-native platforms using Kubernetes, containers, microservices, and related distributed system patterns.
• Hands-on experience with LLM serving or adjacent model-serving patterns, including inference endpoints, routing, scaling, batching, and latency/cost optimization.
• Practical knowledge of API gateway patterns, authentication and authorization, and secure integrations.
• Familiarity with cost attribution and FinOps concepts for cloud and AI workloads.
• Strong track record partnering with product managers and senior technical stakeholders to deliver platform capabilities and roadmaps.
• Excellent communication skills with the ability to explain technical tradeoffs clearly to both technical and non-technical audiences.
• Experience with observability and SRE practices, including metrics, tracing, logging, incident management, and production support.

Preferred Qualifications:

• Direct experience with manufacturing applications, industrial data platforms, or regulated manufacturing environments.
• Experience with agentic AI platforms, agent hosting frameworks, and workflow orchestration tools.
• Familiarity with the broader LLM ecosystem, including model providers, orchestration libraries, and governance frameworks.
• Experience implementing AI gateways, centralized model access controls, policy layers, or audit systems.
• Experience with FinOps tooling and cost-allocation models for platform services.
• Experience shipping developer experience capabilities such as SDKs, CLIs, templates, and documentation.

Soft Skills:

• Excellent analytical and troubleshooting skills.
• Strong verbal and written communication skills.
• Ability to work effectively with global, virtual teams.
• High degree of initiative and self-motivation.
• Ability to handle multiple priorities successfully.
• Team-oriented, with a focus on achieving team goals.
• Strong presentation and public speaking skills.

Thrive

What you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us. careers.amgen.com Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided with reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen