Manufacturing Associate - Downstream

Micro Crispr Pvt. Ltd.; Vapi; On-site; INR 446,400 - 892,800; Full time

Job summary

A leading biotechnology firm based in Gujarat, India seeks a Manufacturing professional to support downstream processing of viral vectors and biologics. You will execute critical manufacturing activities under GMP guidelines, ensuring product purity and compliance. Ideal candidates should have 1–5 years of experience in biologics and hold relevant degrees in Biotechnology or related fields. Join a team dedicated to advancing therapeutic solutions in a cleanroom environment.

Qualifications

• 1–5 years of experience in downstream processing within biologics, vaccines, and monoclonal antibodies.
• M.Sc or B.Sc in Biotechnology, Microbiology, or Biochemistry.
• B.Tech or M.Tech in Biotechnology or Bioprocess.

Responsibilities

• Execute downstream manufacturing activities including filtration and chromatography.
• Prepare buffers and solutions according to approved batch records.
• Operate and maintain downstream equipment.
• Monitor critical process parameters and document activities.
• Troubleshoot process deviations and assist in investigations.

Skills

Downstream processing

Filtration

Chromatography

Problem-solving

Attention to detail

Education

M.Sc in Biotechnology

B.Sc in Microbiology

B.Tech in Biotechnology

M.Tech in Bioprocess

Tools

TFF systems

AKTA chromatography skids

Job description

Overview

(Avoid “Production Executive.” Too small for the gravity of this work.)

🧬 About the Role

Join a team shaping the future of advanced therapeutics, where every purification step brings life-changing treatments closer to patients.

As part of the Manufacturing team, you will support downstream processing of viral vectors and biologics — ensuring purity, consistency, and compliance within a GMP-regulated environment.

This role is ideal for professionals who enjoy translating process science into scalable manufacturing reality.

Responsibilities

• Execute downstream manufacturing activities including filtration, chromatography, and bulk formulation under GMP conditions.
• Prepare buffers, solutions, and process materials as per approved batch records.
• Operate and maintain downstream equipment such as TFF systems, AKTA chromatography skids, depth filters, and associated single-use technologies.
• Monitor critical process parameters and document activities in real time following GDP practices.
• Support technology transfer and process scale-up activities.
• Troubleshoot process deviations and assist in investigations.
• Work closely with Upstream, QA, QC, and Validation teams to ensure smooth batch execution.
• Maintain strict adherence to aseptic practices, safety guidelines, and contamination control strategies.
• Hands-on exposure to purification techniques such as:
• Familiarity with GMP documentation and manufacturing workflows.
• Strong problem-solving mindset with high attention to detail.
• Comfortable working in cleanroom environments.

Qualifications

• 1–5 years of experience in downstream processing within biologics, vaccines, biosimilars, monoclonal antibodies or viral vector.
• M.Sc / B.Sc in Biotechnology, Microbiology, Biochemistry
• B.Tech / M.Tech in Biotechnology or Bioprocess