Computational Biologist

Micro Crispr Pvt. Ltd.; New Delhi; On-site; INR 500,000 - 800,000; Full time

Job summary

A biotechnology firm in New Delhi is seeking a Computational Structural Biologist to work on innovative projects in patient care and medical research. The ideal candidate has a Master's/PhD in Bioinformatics or related fields, expertise in protein engineering, and programming skills in Python or R. This entry-level, full-time position offers the chance to collaborate on cutting-edge research and contribute to significant scientific advancements.

Qualifications

• Proficiency in programming languages such as Python or R, or Java.
• Strong expertise in structural modeling tools.
• Experience in docking and molecular dynamics simulations.

Responsibilities

• Conduct computer-aided drug discovery for hit identification.
• Develop and implement computational models to study protein structures.
• Collaborate with experimental scientists to validate computational predictions.

Skills

Machine learning based platforms for protein engineering and modelling

Generative AI for small molecule and peptide design

Education

Master's degree/PhD in Bioinformatics, Computational structural biology

Tools

Python

R

Java

Rosetta

PyMOL

Chimera

Glide

AutoDock Vina

HADDOCK

AMBER

GROMACS

Desmond

MMPBSA

FEP

Job description

Overview

Job Title: Computational Structural Biologist
Experience: Fresher to 2 years

JD for Computational Structural Biology Team

We are seeking a talented and enthusiastic COMPUTATIONAL STRUCTURAL BIOLOGIST to join our innovative team. As part of our team, you will have the opportunity to work on cutting-edge projects that have a significant impact on patient care and medical research.

Responsibilities

• Computer aided drug discovery for hit identification.
• de novo protein design and computational evaluation
• Develop and implement computational models to study protein structures.
• Computational antibody engineering
• Conduct molecular docking, dynamics simulations, and free-energy calculations.
• Experience in handling protein structure prediction tools
• Collaborate with experimental scientists to validate computational predictions.
• Maintain and optimize computational pipelines for high-throughput analysis.
• Data Analysis and Interpretation
• Write and present research findings in scientific reports and publications/patents.

Required Skills

• Machine learning based platforms for protein engineering and modelling (AlphaFold, RFDiffusion, RosettaFold)
• Generative AI for small molecule and peptide design

Qualifications

• Master's degree/PhD in Bioinformatics, Computational structural biology
• Proficiency in programming languages such as Python or R, or Java.
• Strong expertise in structural modeling tools (e.g., Rosetta, PyMOL, Chimera).
• Experience in docking (Glide, AutoDock Vina, HADDOCK) and molecular dynamics simulations (AMBER, GROMACS. Desmond) etc
• Experience in downstream analysis tools such as MMPBSA, FEP
• Immunoinformatic, computational protein engineering tools

Soft Skills

• Ability to work independently and collaboratively in a team-based environment.
• Excellent problem-solving skills and the ability to think critically and analytically.
• Emphasize interpersonal and problem-solving skills.
• Strong communication and teamwork abilities.
• Critical thinking and attention to detail.
• Ability to manage multiple projects and meet deadlines

Seniority level

• Entry level

Employment type

• Full-time

Job function

• Research