BRL (Research Associate) - R&D - Analytical - 2

USV PRIVATE LIMITED; Maharashtra; On-site; INR 1,200,000 - 1,800,000; Full time

Job summary

USV PRIVATE LIMITED invites an experienced analytical development professional to join the BRL and own analytical deliverables for Biologics projects across markets. You will lead method development, qualification, technology transfer, and characterization, with hands-on work on MS, HPLC/UPLC, CE, and related chromatography and electrophoresis techniques.

The role requires 2–5 years in an analytical development lab and a biotech degree; familiarity with data integrity and report review is

Qualifications

• 2–5 years of experience in an analytical development laboratory setting.
• Hands-on experience in HPLC and UPLC is mandatory; knowledge of RP, HIC, IEX, SEC is required.
• Capillary electrophoresis techniques (CIEF, CZE, CE-SDS) experience is required.
• Higher order structure analysis (DSC, CD, Fluorescence, FTIR) is an advantage.
• Experience with biotherapeutic proteins (monoclonal antibodies, Fc fusion, biosimilars) is preferred.
• Method Development and Qualification experience is required.

Responsibilities

• Plan and execute experiments with focus on Mass Spectrometry, HPLC, UPLC, and CE-based analysis.
• Apply analytical techniques including chromatography, electrophoresis, spectrophotometry, and colorimetric assays for Biotherapeutics.
• Perform analytical activities per established systems and procedures.
• Maintain target dates for all activities.
• Ensure data integrity during analysis processes.
• Prepare and review technical reports and assist with troubleshooting lab instrumentation.
• Communicate analytical data effectively with team members.

Skills

Mass Spectrometry

HPLC

UPLC

CE-based Analysis

Chromatography

Electrophoresis

Spectrophotometry

Colorimetric Assays

Data Integrity

Education

BSc./MSc. Biotechnology

B.Tech/MTech Biotechnology

Tools

DSC

CD Spectroscopy

FTIR

Fluorescence Spectroscopy

Job description

Role Objective: Will work in the Analytical Development Lab of BRL, taking responsibility for the analytical deliverables of Biologics Projects for all markets. Deliverables involve, but are not limited to, Method Development, Qualification, Technology transfer, Biosimilarity assessment, Forced degradation, and Characterization activities.

Key Responsibilities

• Responsible for the independent planning and execution of experiments, with a major focus on Mass Spectrometry, HPLC, UPLC, and CE-based analysis.
• Apply analytical techniques including, but not limited to, Chromatography, Electrophoresis, Spectrophotometry, and Colorimetric assays for Biotherapeutics.
• Perform assigned analytical activities by following established systems and procedures.
• Maintain target dates for all assigned analytical activities.
• Maintain strict data integrity during all analysis processes.
• Prepare and review technical reports and contribute directly to troubleshooting efforts required for laboratory instrumentation.
• Communicate effectively with other team members and teams regarding the generated analytical data.

STAKEHOLDER INTERACTION

Type of Interaction: Internal

• Interaction with: Other team members and teams.
• Nature of Interaction: Communicate effectively regarding the analytical data.

Type of Interaction: External :

• Interaction with: Not explicitly specified in the vacancy details.
• Nature of Interaction: Not explicitly specified in the vacancy details.

JOB REQUIREMENTS Professional Experience And Relevant Skills

• Experience: 2-5 years of experience within an analytical development laboratory setting.
• Skills: Hands-on experience in HPLC and UPLC is mandatory. Knowledge and hands-on experience of different chromatography modes like RP, HIC, IEX, SEC, etc., is required. Knowledge and hands-on experience of different capillary electrophoresis techniques (CIEF, CZE, CE-SDS, etc.) is required. Hands-on experience with Higher order structure analysis (DSC, CD, Fluorescence, FTIR, etc.) is an advantage.
• Technical Expertise: Experience working on biotherapeutic proteins like monoclonal antibodies, Fc fusion, peptibody, or any candidate biosimilars is required. Method Development and Qualification experience is a must. An understanding of analytical deliverables involving CQA, QTPP, Analytical similarity, Forced degradation studies, and Specifications setting is preferred.

Academic Qualifications & Certifications

• Educational Qualification: BSc./MSc. Biotechnology or B.Tech/Mtech. Biotechnology