Senior Manager, Engineering and Reliability

BioMarin Pharmaceutical Inc.; Cork; Hybrid; EUR 120,000 - 150,000; Full time

Job summary

BioMarin Shanbally site in Cork is seeking a Senior Manager – Engineering and Reliability to lead maintenance, asset lifecycle management and calibration programmes. The role drives equipment uptime, reliability and safety, coordinating with global teams on capital projects and asset strategy.

The position supports Drug Substance Manufacturing, packaging, QC labs and utilities, requiring deep biopharma experience and strong leadership in reliability engineering.

Qualifications

• Minimum of 15 years’ experience in the bio-pharmaceutical industry.
• Proven leadership in maintenance and reliability programs.
• Strong knowledge of asset lifecycle management and calibration programs.
• Experience with cGMP regulations and safety practices.

Responsibilities

• Lead ALM program and align capital plans with policy and global partners.
• Oversee calibration of GMP, safety and environmental instrumentation.
• Manage spare parts, consumables and the CMMS system.
• Drive asset resiliency and reliability improvements across the site.
• Collaborate with global functions on capital projects for Shanbally.

Skills

Asset Lifecycle Management

Maintenance leadership

Reliability engineering

CMMS

Education

Relevant third level qualification in Science, Engineering or related discipline

Tools

CMMS

Electrical infrastructure

Biotech facility design

Job description

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions.

Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions.

Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world‑class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world.

About Technical Operations

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting‑edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients.

Senior Manager Engineering and Reliability

Location Cork

Hybrid – 3 days On Site

Closing Date Friday 30th October 2026

The Role

The Senior Manager – Engineering and Reliability reports to the Associate Director, Engineering Operationsand is responsible for site maintenance practices and reliability systems across the Shanbally plant.

Role Summary

The Senior Manager – Engineering and Reliability is responsible for implementing an asset care strategy at BioMarin Shanbally in order to maximize equipment uptime and increasing operations resiliency.

He/She will be responsible for the leadership and technical oversight of the Reliability, Asset Lifecyle management, calibration programmes and Electrical infrastructure

The scope of this role will cover all maintenance, facility & utility engineering activities on the site in support of Drug Substance Manufacturing, Package and Labelling, Warehouse & Dispensing, QC and MSAT labs, Office areas & Fill Finish operations.

Responsibilities

• Responsible for site Asset Lifecycle Management (ALM) and aligning the capital plan and execution with the ALM policy, liaising and developing relationships locally and globally.
• Responsible for the calibration program for all GMP, Safety and environmental related instrumentation and equipment is implemented in a compliant state
• Responsible for site spare parts and consumables to manage in a timely and cost-effective manner
• Responsible as system owner for Electrical Infrastructure and Refrigerant systems
• Responsible for the CMMS system on the Shanbally, liaising with global functions and support all departments with regard to it use, while ensure it meets the needs of the reliability Programme
• Ensure that milestones for the ALM and Reliability Programmes are met (e.g. Monthly metrics/trend KPIs, Reliability Self assessments and Asset Replacement Assessment)
• Ensure maintenance/reliability practices and systems are adhered to and to identify and implement improvements to improve the overall efficiency and effectiveness of the maintenance and utility operations
• Ensure Preventative and Predictive Maintenance programmes are effective and are deployed with a reliability mindset, utilising advances technology where applicable
• Drive, promote and instil a culture of asset resiliency, care and optimisation
• Challenging engineering practices to ensure efficient process and system
• Assist all areas of maintenance execution to eliminate repeat issues, compliance risks and inefficiencies
• Works with the site Capital Projects group with execution of capital projects from the initiation/concept phase through to handover of the project. Working with Capital strategy on initiation /concept of key strategic projects for the Shanbally site.
• A broad knowledge of Health, Safety, and Environmental requirements with a demonstrated commitment to safety
• Collaboration/Influence Management, Decision Making, Results Orientation
• Maintain documentation and management and control systems in compliance with cGMP regulations and training instructions
• Support the Maintenance, Facilities & Utilities function with regard to Safety, Quality or Asset management audits.
• Sound technical knowledge of design of biotech facilities incl process, equipment, piping and other key design disciplines
• Set objectives for the Engineering and Reliability team and ensure measurement system is in place to track performance vs plans

Experience

• A minimum of 15 years’ experience in the bio-pharmaceutical industry with strong technical, management and/or maintenance experience

Education

• A relevant third level qualification in Science, Engineering or related discipline is preferred.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

If you have a disability and believe you need a reasonable accommodation in order to search for a job opening or apply for a position, email [e-mail] with your request.
This email address is not for general employment inquiries or correspondence. We will only respond to those requests that are related to the accessibility of the online application system due to a disability.

BioMarin Pharmaceutical does not accept unsolicited resumes from recruiters or agencies and we will not be responsible for any fees related to resumes that are unsolicited. We handle all recruiting through our Talent Acquisition team – please do not contact hiring managers directly. Agencies who wish to offer their services to BioMarin Pharmaceutical may contact us at [e-mail] .
Applicants, please do not use this email address to submit resumes – if you do so, you will be redirected to apply through the website.