Lead Analytical Scientist - Methods, Validation & Transfer

Alexion Pharma Spain S.L.; Dublin; Hybrid; EUR 60,000 - 90,000; Full time

Job summary

AstraZeneca in Dublin, Ireland, is seeking a Senior Scientist in Analytical Sciences & Technology to lead method development, validation, and tech transfers. The role focuses on robustness, regulatory readiness, and manufacturing reliability, partnering with Manufacturing, Development, Quality, Regulatory, Supply and Commercial to shape analytical strategy and deliver results that matter.

You will design studies end-to-end, troubleshoot investigations, author regulatory content, and mentor

Qualifications

• Bachelor's degree in biochemistry, chemistry, microbiology or a relevant scientific discipline.
• 5+ years experience in an analytical role in a bio-pharmaceutical manufacturing or development area.
• Experience with analytical method development and optimisation.
• Proven knowledge of cGMP/GLP requirements and implementation of standard methodologies to ensure technical excellence.

Responsibilities

• Design, refine, and stress-test analytical methods to improve robustness, sensitivity, and throughput.
• Author and execute protocols, analyze results, and lead method transfers.
• Plan and run studies end-to-end from protocol to data reporting.
• Perform method capability and trending to establish control strategies.
• Lead or support analytical investigations and problem-solving to unblock manufacturing issues.
• Author analytical content for technical reports and regulatory submissions; train new personnel.
• Provide hands-on technical leadership and maintain a safe, compliant lab environment.
• Support critical lab studies outside standard hours when needed.

Skills

Analytical Method Development

cGMP/GLP Knowledge

Data Trending & Analysis

Cross-functional Collaboration

Education

Bachelor's degree in biochemistry/chemistry/microbiology

Masters degree preferred

Job description

AstraZeneca in Dublin, Ireland, is seeking a Senior Scientist in Analytical Sciences & Technology to lead method development, validation, and tech transfers. The role focuses on robustness, regulatory readiness, and manufacturing reliability, partnering with Manufacturing, Development, Quality, Regulatory, Supply and Commercial to shape analytical strategy and deliver results that matter.

You will design studies end-to-end, troubleshoot investigations, author regulatory content, and mentor