Trials Manager | The Royal Marsden NHS Foundation Trust

The Royal Marsden NHS Foundation Trust; City Of London; Hybrid; GBP 40,000 - 55,000; Full time

Job summary

A leading cancer research hospital in the UK is looking for a Trial Manager to coordinate clinical trials within the GI & Lymphoma Unit. Candidates should have a strong background in clinical research, with experience in regulatory submissions and approvals. This role offers opportunities for hybrid working after training and is integral to advancing cancer research. Applicants require a first degree in a health-related field and must demonstrate excellent organizational skills.

Benefits

Dynamic working environment

Learning and development opportunities

Flexible working requests

Qualifications

• In-depth understanding and at least three years of experience with Good Clinical Practice.
• Ability to manage regulatory submission and approvals under pressure.
• Experience in supporting trial set-up and handling data monitoring.

Responsibilities

• Coordinate clinical trials setup and conduct.
• Contribute to trial design and protocol development.
• Prepare and submit ethics and regulatory applications.

Skills

Good Clinical Practice

Data Protection

Research Governance

Interpersonal Skills

Trial Co-ordination

Education

First degree in life science or health related subject

Job description

A very exciting opportunity has arisen in the GI & Lymphoma Unit at the Royal Marsden Hospital for a Trial Manager. You will need to be experienced and confident with regulatory submission and approval processes, clinical trial costing being self- motivated, pro-active and well organised to work within this friendly team in a highly pressurised environment at the forefront of research of GI & Lymphoma research.

Responsibilities

• Coordinate the set-up and conduct of clinical trials and clinical research projects.
• Contribute to clinical trial design, protocol development and funding applications together with CI, statistician and other members of the team, under the supervision of Senior Trial Managers and Project Managers members.
• Input into clinical trial protocols, prepare funding applications for new study proposals and prepare clinical trial budgets, under the supervision of the senior team members.
• Contribute to preparation of essential clinical trials documents, including protocol, patient information sheets in collaboration with Chief Investigator (CI), Senior Trial Manager, Clinical Fellow etc.
• Contribute to preparation of trial documentation e.g. trial guidance notes, case report forms (CRFs), monitoring plans, in collaboration with relevant members of the Trial Management team including the CI, clinical fellow (where relevant) Clinical Trial Database Programmer (CTDP) and Statistician.
• Contribute to preparation and submission of applications for ethics, regulatory, Sponsor, and other approvals that may be required in order to conduct the clinical trial.
• Ensure all the required approvals and agreements are in place before the trial opens to recruitment.
• Ensure clinical supplies or equipment are available and distributed appropriately.
• Set-up trial specific procedures including monitoring plans in accordance with RM (in it’s capacity as Sponsor) SOPs to ensure the efficient management of the trial.
• Set-up electronic Trial Master File and support research sites in the setup and maintenance of electronic Investigator Site Files.
• Coordinate set-up of trial oversight committees and charters in collaboration with CI, statistician and other members of the team for Sponsored studies.
• Plan and perform site initiation visits ensuring sites have all applicable documentation in place and that principal investigators and site staff understand the protocol and their responsibilities within the trial.

Qualifications

• Applicant should hold a first degree in a life science or health related subject and have an in depth understanding and at least three years’ working experience of Good Clinical Practice, Data Protection and Research Governance.
• Excellent interpersonal skills are essential to work to the high standards across a variety of tasks with constant regard to all regulatory requirements and Trust Standard Operating Procedures.
• Experience is required to enable you to take a key role in setting up trials as well as supporting the set-up of participating sites, data handling/monitoring and trial co-ordination.
• Role requires a clinical research professional who has extensive experience in clinical trials conduct ideally in different settings (Pharma, Academic) and familiarity with the regulatory environment surrounding clinical trials and the implementation of a quality management system as it pertains to clinical trial conduct.

Location

Post holder will be based at Sutton within the Oak Cancer Centre, a new research and treatment facility, funded by The Royal Marsden Cancer Charity. Occasional travel to our Chelsea location and /or other UK clinical trial sites will be required as the projects require. There is potential for Hybrid working after training is completed.

About Royal Marsden

The Royal Marsden NHS Foundation Trust is a world-leading cancer centre. Our role is to offer our patients the best cancer care available anywhere in the world, and to continue to make a global contribution to finding better ways of diagnosing and treating cancer. We employ over 4,500 staff in a diverse range of careers including nursing, medical, science, radiography, pharmacy, occupational therapy, finance and administrative services. We have two hospitals – one in Chelsea, London, and one in Sutton, Surrey – as well as a Medical Daycare Unit in Kingston Hospital.

At The Royal Marsden, we deal with cancer every day, so we understand how valuable life is. When people entrust their lives to us, they have the right to demand the very best. That's why the pursuit of excellence lies at the heart of everything we do.

At the heart of the hospital is our dedicated team. We offer a stimulating and dynamic working environment, a wide range of staff benefits, learning and development opportunities and clear career pathways. There are opportunities to work flexibly across a range of areas and specialities and we welcome flexible working requests from point of hire to support employees work life balance. We are looking for employees who aspire to excellence, share our values and can play a crucial role in our on-going achievements.

Closing

This advert closes on Friday 21 Nov 2025