Translational and Precision Medicine Lead

Chiesi Farmaceutici S.p.A.; England; Hybrid; GBP 70,000 - 100,000; Full time

Job summary

A leading pharmaceutical company is seeking a Translational and Precision Medicine Lead to lead clinical studies in the UK. The role requires over 5 years of experience in clinical development and a strong background in translational research. Candidates with an MD or PhD in biomedical sciences are preferred. The company offers a supportive environment focused on work-life balance and employee wellbeing, with options for remote work and flexible schedules.

Benefits

Flexible working approach

Remote working options

Support in the relocation process

Tax assistance service for foreign colleagues

Qualifications

• 5+ years of experience in clinical development, translational research, or related fields.
• Relevant experience in clinical or academic research in rare diseases is a plus.

Responsibilities

• Lead translational & precision medicine studies within clinical development.
• Represent GRD Clinical Development for regulatory & scientific interactions.
• Design and implement studies to validate new technologies for clinical programs.

Skills

Leadership and social influence

Strategic thinking

Education

MD or equivalent, or PhD in biomedical science

PharmD or Master’s Degree with relevant experience

Job description

Translational and Precision Medicine Lead

Department: GRD Clinical Development

Business Area: R&D, Pharmacovigilance & Regulatory Affairs

Job Type: Direct Employee

Contract Type: Permanent

Location: Europe - remote, GB

About us

Based in Parma, Italy, Chiesi is an international research-focused pharmaceutical and healthcare group with 90 years’ experience, operating in 31 countries with more than 7,000 employees (Chiesi Group). To achieve its mission of improving people’s quality of life by acting responsibly towards society and the environment, the Group researches, develops and markets innovative drugs in its main therapeutic areas: Discover more here

We are proud to have been awarded with B Corp Certification, a recognition of high social and environmental standards. We are a reliable company that adopts and promotes a transparent and ethical behavior at all levels.

We believe that the success of Chiesi is built and shaped by our people and our strong set of shared Values and Behaviors. Our people make a critical difference to our success, which is why it is vital that we attract and retain the right talent who will continue to enrich our culture by living and breathing our values and behaviors.

We are committed to embrace diversity, inclusion and equal opportunities. In fact, we are a global family made up of different cultures, different genders, generations, ethnicities, abilities, sexual identities and many other enriching diversities.

Chiesi Global Rare Diseases is a Chiesi Group’s business unit established in February 2020 and focused on research, development and commercialization of treatments and patient support services for rare and ultra-rare disorders, many of whom have limited or no treatments available.

This unit is based in Boston, Massachusetts, with a strong synergy with the headquarters in Parma.

Rare unit has a focus on research and product development for lysosomal storage diseases, rare hematology, ophthalmology disorders and rare immunodeficiencies. The unit is also a dedicated partner with global leaders in scientific research, patient advocacy and care. Discover more here.

Purpose

The role assures that translational & precision medicine milestones and principles are implemented into the clinical development plans

The role leads translational & precision medicine studies within development programs incorporating quality, pharmacodynamics, bioinformatics, and bioanalytical analyses

The role acts as the resident translational medicine expert within GRD Clinical Development for specific disease indications, building the GRD Clinical Development competencies, relative to all medical/scientific aspects and acting as clinical interface with the preclinical experts/representatives to steer translational medicine science across the R&D

Main Responsibilities

• Represents the Product(s) Clinical Expertise for translational & precision medicine matters for specific disease indications inside and outside the company
• Acts as Subject Matter Expert in the area of translational & precision medicine for specific disease indications, maintaining and enhancing knowledge in relevant therapeutic or technical matters
• Represents GRD Clinical Development and R&D for regulatory & scientific interactions, patient registries, biomarker consortia, workshops for translational & precision medicine matters
• Supports the Clinical Evaluation of external opportunities considering Chiesi’s in-licensing strategy, in collaboration with other members of the Clinical team as well as
• Liaises with the pre-clinical experts to steer translational & precision medicine science across the R&D
• Designs and leads the implementation of feasibility/exploratory studies in humans to validate new technologies to be implemented in clinical programs for translational assets when needed, and leads the development and implementation of bioanalytical and bioinformatics studies to understand the mechanisms of action of drugs by multi-dimensional–omics data generation
• Designs and leads the development of studies aimed to identify and validate biomarkers for clinical studies endpoint as well as for patient stratification, through integrated analysis of high-throughput molecular data and clinical phenotypes
• Designs and leads the implementation of studies aimed to generate new hypotheses from multi-platform and diverse datasets by employing data science and computational biology approaches
• Builds relationships with scientific leaders, KOLs, academic partners and scientific networks to develop specific hypothesis-driven collaborations to complement internal effort

Experience Required

5+ years of experience in industry are required, specifically in clinical development, translational research or related fields

Relevant experience in clinical or academic research in rare diseases and/or advanced therapeutics will be considered a plus

Education

MD or equivalent with experience in clinical research or PhD in biomedical science are required

PharmD or Master’s Degree, with long-standing, relevant experience to the role, may be considered as well

Soft Skills

• Leadership and social influence
• Strategic thinking

What we offer

You would join a dynamic, fast-growing, challenging and friendly environment.
In Chiesi we firmly believe that our people are our most valuable asset, that is why we invest in continuous training, learning and development. Therefore, we strive to continuously promote and satisfy development needs, paying particular attention to the quality of our working environment and collective well-being.
We want our people to come to work happy every day, and we know how important it is to find the right work-life balance in order to be able to give our best. That is why we offer flexible working approach, remote working, support in the relocation process, tax assistance service for foreign colleagues and many other people-care services.