Technical Product Lead, Manufacturing Execution System

Oxford Nanopore Technologies; Oxford; On-site; GBP 65,000 - 85,000; Full time

Job summary

Oxford Nanopore Technologies is seeking a Technical Product Lead for their Manufacturing Execution System (MES). This role involves managing the operation and lifecycle of the NoMuda VisualFactory platform, ensuring integration with existing systems, and collaborating with development teams. The ideal candidate should have experience with digital manufacturing platforms and SaaS, along with strong communication skills. The position is based in Oxford, England, and plays a crucial role in enhancing the company's digital manufacturing strategy.

Qualifications

• Experience managing complex, integrated digital manufacturing platforms.
• Solid understanding of software architecture, integrations, and data management.
• Experience working with software development teams in Agile environments.

Responsibilities

• Drive effective integration between existing systems and new MES.
• Own the lifecycle management of NoMuda VisualFactory.
• Collaborate with development teams and process engineers.

Skills

Managing complex, integrated digital manufacturing platforms

Managing SaaS platforms

Software architecture

Agile or hybrid environments

Working with manufacturing process engineers

Strong stakeholder engagement

Communication skills

Job description

Job Description

Technical Product Lead, Manufacturing Execution System (MES)

Oxford Nanopore

Oxford Nanopore has developed a new generation of nanopore-based sensing technology for faster, information-rich, accessible and affordable molecular analysis. The technology is used to understand and characterise the biology of humans, animals, plants, bacteria, viruses, and diseases such as cancer. By enabling biological insights, we strive to improve life on Earth and beyond.

The Role

We are seeking a Technical Product Lead to take ownership of our Manufacturing Execution System (MES), supporting the manufacture of our sequencing products.

This role will be responsible for the technical integration, operational effectiveness, compliance, and technical coherence of our newly commissioned MES SaaS platform, NoMuda VisualFactory.

Reporting to the Manufacturing Platform Owner, you will work closely with our in house development teams responsible for bespoke systems supporting tracking, traceability, and control across complex manufacturing processes.

The MES platform is central to our digital manufacturing strategy, enabling manufacturing process engineers to safely and consistently self configure workflows while ensuring compliance with GAMP standards and seamless integration with internal systems.

You will collaborate closely with NoMuda implementation and support teams, internal software engineering teams, manufacturing process engineers across Production and Tech Transfer, and Quality, Validation, and Regulatory stakeholders.

Key Responsibilities

MES Ownership & Operations

• Drive an effective, coherent integration between existing manufacturing systems and the new MES, NoMuda Visual Factory
• Own the operation and lifecycle management of the NoMuda VisualFactory MES platform
• Ensure platform availability, performance, security, and data integrity of the MES
• Ensure operational processes, including support, incident management, change control, and release coordination, conforms to ONT's internal processes
• Act as the primary technical owner for incidents and enhancements for VisualFactory, and engagement with NoMuda

Technical Coherence

• Maintain technical coherence across VisualFactory and integrated in-house systems
• Define and govern integration patterns, data flows, APIs, and event-driven interactions
• Identify and mitigate technical, architectural, and operational risks throughout the system’s lifecycle

Configuration Strategy & SME Enablement

• Collaborate with the Manufacturing Platform Owner to define and implement patterns for self-service configuration by process engineers, to ensure solutions are scalable, maintainable, and compliant

Continuous Improvement & Data-Driven Decisions

• Work alongside software development teams to guide design decisions and implementation approaches
• Identify and implement process improvements and operational efficiencies
• Collect and analyse platform usage statistics and user feedback
• Monitor key performance indicators (KPIs) for platform health, adoption, and value

Required Skills & Experience

Technical & Platform Experience

• Experience managing complex, integrated digital manufacturing platforms
• Experience managing SaaS platforms
• Solid understanding of software architecture, integrations, and data management
• Experience working with software development teams (Agile or hybrid environments)
• Experience working directly with manufacturing process engineers

Manufacturing & Collaboration Skills

• Experience working directly with manufacturing SMEs and process engineers
• Experience working collaboratively with SaaS vendors
• Strong stakeholder engagement and communication skills across technical and non-technical audiences

Desirable Experience

• Strong understanding of manufacturing systems in regulated environments
• Experience of complex medical device, biologics, biopharma manufacturing or development.
• Experience working with NoMuda VisualFactory or similar low-code MES platforms
• Experience with compliance standards such as GAMP, ISO 13485, or computer system validation (CSV) in medical device or life sciences environments

Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

About Us

Oxford Nanopore Technologies: Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis. The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins. The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments. With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.