Technical Lead, Medicines Safety Technologies

The Medicines And Healthcare Products Regulatory Agency; Greater London; On-site; GBP 78,000 - 88,000; Full time

Job summary

The Medicines And Healthcare Products Regulatory Agency in the United Kingdom is seeking an experienced Technical Lead, Medicines Safety Technologies to join our Safety and Surveillance group.

You will lead evaluation of AI-enabled medicines safety, collaborate with experts across MHRA, industry and academia, and contribute to regulatory science and decision-making.

Qualifications

• Postgraduate qualification (MSc, PhD or equivalent) in AI, computational biology, pharmacology, toxicology or data science.
• Degree in a relevant scientific, technical or healthcare discipline.
• Experience evaluating scientific evidence and AI methodologies.

Responsibilities

• Provide senior scientific and technical leadership for the “Beyond ADMET: AI for Medicines Safety” Sandbox programme.
• Lead evaluation of emerging AI methods, data sets and evidence for medicines safety and regulatory decision‑making.
• Collaborate with MHRA, industry, academia and government to share expertise and drive impact.
• Represent the programme through technical engagement and thought leadership.

Skills

Artificial Intelligence

Machine Learning

Healthcare data science

Pharmacology

Toxicology

Drug development

Safety science

NAMs

Regulatory science

Education

MSc or PhD in a relevant field

Postgraduate qualification in AI, computational biology, pharmacology, toxicology, data science or related discipline

Job description

The MHRA is transforming. Through enabling innovation, making the right judgements of the benefits and risks of medical products and forging the right partnerships in the UK and internationally, it aims to deliver world class regulation and improved outcomes for UK patients.

We are currently looking for experienced Technical Lead, Medicines Safety Technologies to join our Benefit/Risk Evaluation Team I in the Safety and Surveillance group.

Within a week of working here, your day could look like this: Responsible for providing senior scientific and technical leadership for the “Beyond ADMET: AI for Medicines Safety” Sandbox programme, ensuring programme activities are scientifically robust, technically credible and aligned with regulatory objectives.

The successful candidate will work in partnership with the Head, AI for Medicines Safety to ensure the programme benefits from complementary expertise across artificial intelligence, healthcare data science, toxicology, pharmacology, medicines development and regulatory science.

You will lead the evaluation of emerging methodologies, technologies, datasets and evidence relevant to AI-enabled medicines development, safety assessment and regulatory decision‑making.

You will build and maintain strong relationships with experts across the MHRA, industry, academia and government, representing the programme through technical engagement, collaboration and thought leadership activities.

The successful candidate will have a degree in a relevant scientific, technical or healthcare discipline (or equivalent experience).

• - Postgraduate qualification (MSc, PhD or equivalent experience) in a relevant field such as artificial intelligence, computational biology, pharmacology, toxicology, data science, bioinformatics, pharmaceutical sciences or a related discipline.
• - Recognised technical expertise in either: Pharmacology, Toxicology, Drug Development, Safety Science, New Approach Methodologies (NAMs) or related disciplines, OR AI, Machine Learning, Healthcare Data Science, or related disciplines.
• - Ability to critically evaluate scientific evidence, AI methodologies, model performance and validation approaches.

Our successful candidate will have:

• o Pre-clinical assessment, toxicology and New Approach Methodologies (NAMs)
• o Artificial Intelligence and Machine Learning
• o Healthcare data science and computational modelling
• o Pharmacology, drug discovery or development or related scientific areas.

• - Experience applying scientific and technical expertise to complex regulatory, healthcare, research or industry challenges; and evaluating scientific evidence and translating findings into practical recommendations and actions.
• - Experience working with multidisciplinary teams involving scientific, technical and non-technical stakeholders, and engaging effectively with external stakeholders, including academia, industry and research organisations.
• - Experience preparing technical reports, scientific assessments, briefings, publications or regulatory submissions.

Closing date: 15 November 2026

Technical Lead, Medicines Safety Technologies - £78,230 - £87,809 p.a. + benefits - Civil Service Jobs - GOV.UK

£78,230. Grade 6