Synthetic Organic & Medicinal Chemist — Drug Discovery CRO

Sygnature Discovery North America; Nottingham; Vor Ort; GBP 60.000 - 90.000; Vollzeit

Benefits dieser Stelle

25 days annual leave (plus bank hols)

Private Medical Insurance

Life Insurance

Employee Assistance Programme

Enhanced Family Friendly Policies

Sygnature Group Pension Scheme

1 paid volunteer day per year

Zusammenfassung

Sygnature Discovery is seeking talented synthetic organic and medicinal chemists to join our Alderley Park-based team on a six-month fixed-term basis. We value candidates who can join on short notice and bring a strong track record in multi-step synthesis to drug discovery projects.

As part of a dynamic, multidisciplinary CRO environment, you will design and implement complex synthetic routes, collaborate across disciplines, and contribute to high-quality outputs for diverse clients.

Qualifikationen

• PhD or equivalent in Organic/Medicinal Chemistry, or a BSc/MSc with several years of industrial drug discovery experience.
• Ability to time-manage the implementation of multiple synthetic sequences in parallel.
• Broad experience performing common organic transformations on a variety of scales, and utilisation of both 1D and 2D NMR techniques.
• Excellent verbal and written communication skills, as well as the ability to work well within a team environment.
• Experience within a CRO environment is desirable, with the ability to build strong relationships and collaborate effectively with external clients and stakeholders.

Aufgaben

• Design, plan and execute multi-step synthetic chemistry routes to deliver novel target compounds in support of client and internal drug discovery projects, working to agreed timelines and project milestones.
• Independently analyse experimental results, troubleshoot synthetic challenges and propose alternative strategies to drive project progression and overcome technical obstacles.
• Work closely within a multidisciplinary team to understand project objectives, contribute scientific ideas and ensure chemistry activities support wider goals.
• Maintain accurate electronic laboratory notebook (ELN) records and communicate scientific findings through project meetings, technical presentations, client updates, reports, patents and scientific publications where appropriate.
• Utilise a broad range of synthetic chemistry techniques, analytical instrumentation, scientific databases and literature resources to design efficient synthetic routes and support decision making.
• Balance laboratory activities with departmental responsibilities while delivering high-quality scientific output in a fast-paced CRO environment.

Kenntnisse

Multi-step synthesis planning

NMR techniques

Analytical data interpretation

Team collaboration

Verbal and written communication

Ausbildung

PhD in Organic/Medicinal Chemistry

BSc/MSc in Chemistry with industry drug discovery experience

Jobbeschreibung

Sygnature Discovery is seeking talented synthetic organic and medicinal chemists to join our Alderley Park-based team on a six-month fixed-term basis. We value candidates who can join on short notice and bring a strong track record in multi-step synthesis to drug discovery projects.

As part of a dynamic, multidisciplinary CRO environment, you will design and implement complex synthetic routes, collaborate across disciplines, and contribute to high-quality outputs for diverse clients.